TF-1 In Vitro Calcein AM Cytotoxic Assay (Cell Viability)

CAT#: ITS-1122-YF1687
Target Cell Organism: Human
Target Cell Name: TF-1
Assay Type: Cell Viability/Cytotoxicity and Antiproliferative Assays
Assay Overview
This assay is to provide TF-1-based In Vitro Calcein AM Cytotoxic Assay (Cell Viability) to accelerate our client's oncology projects. The assay will be customized according to the specific requirements. Please contact our scientists to discuss more details.
Target Cell Name
TF-1
Target Cell Organism
Human
Target Cell Background
TF-1 erythroblasts are isolated from bone marrow derived from a 35-year-old Asian male with severe pancytopenia in 1987. The cells provide a good system for investigating the proliferation and differentiation of myeloid progenitor cells.
Related Diseases
Erythroleukemia
Research Area
Oncology
Assay Name
In Vitro Calcein AM Cytotoxic Assay (Cell Viability)
Short Description
TF-1-cell based In Vitro Calcein AM Cytotoxic Assay (Cell Viability)
Assay Description
Calcein AM is another non-fluorescent cell permeable dye, which is converted to green-fluorescent calcein by viable intracellular esterases. Calcein violet AM, calcein red-orange, Oregon green 488 and 5-CFDA-AM are other examples of dyes used to monitor cell viability based on esterase activity in viable cells.
Assay Type
Cell Viability/Cytotoxicity and Antiproliferative Assays
Assay Type Details
Uncontrolled proliferation is one of the main features of cancer cells. Cell-based in vitro assays are employed to determine whether test molecules possess direct cytotoxic/antiproliferative effects in cancer cells.
Assay Subtype
Cell Viability Assay
Assay MOA
Cell-based Viability Assays Based on Cellular Enzymes and Proteins
For Research Use Only | Not For Clinical Use
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