Thiamine Oxidase-targeted RNA Modification and Metabolomics Analysis Tool
CAT#: ITS-0524-CR160
Cell Type: M1 macrophages
RNA writers: DNMT2
RNA readers: ALYREF
RNA erasers: ALKBH1
Enzymes: HATs
RNA types: mRNAs
Modification: ac4C
RNA editing: A to I
Short Description
This product is a Thiamine oxidase-targeted RNA modification and metabolomics analysis tool based on the ac4C (DNMT2-ALYREF-ALKBH1-HATs-spacer C9) modification and Glycolysis-mediated (hnRNPs-Lactyl-CoA-ADP) metabolic analysis system.
RNA writers
DNMT2
RNA readers
ALYREF
RNA erasers
ALKBH1
Enzymes
HATs
RNA types
mRNAs
Modification
ac4C
Label
spacer C9
RNA editing
A to I
Cell Type
M1 macrophages
Oligonucleotide
2'-MOE, GalNAc
RNA Construction
mRNAs-ac4C-DNMT2-ALYREF-ALKBH1-HATs-spacer C9
Substrates
Lactyl-CoA
Cofactors
ADP
Pathway
Glycolysis
Epigenetic regulator
SMARCA4 overexpression
Metabolic alteration
Upregulating fatty acids synthesis
Targeting diseases
Acute Myeloid Leukemia
RNA-binding proteins
hnRNPs
Metabolic Reprogramming
Glycolysis-hnRNPs-Lactyl-CoA-ADP
Target
Thiamine oxidase
Alternative Names
Thiamine oxidase
Format
Liquid
Shipping
All ordered products are shipped from Fedex or UPS.
Handling Advice
Prevent prolonged exposure to light.
Storage
Recommended long-term storage in - 20 ° C, to ensure the longest shelf life of products.