TOMM40-targeted RNA Modification and Metabolomics Analysis Tool

CAT#: ITS-0524-CR322
Cell Type: CD4⁺ T Cells
RNA writers: TRMT6/61A
RNA readers: YTHDF1/2/3
RNA erasers: ALKBH7
Enzymes: PSAT1
RNA types: mRNAs
Modification: ac4C
RNA editing: A to I
Short Description
This product is a TOMM40-targeted RNA modification and metabolomics analysis tool based on the ac4C (TRMT6/61A-YTHDF1/2/3-ALKBH7-PSAT1-spacer C18) modification and Mevalonate pathway-mediated (α-synuclein-SAM-ADP) metabolic analysis system.
RNA writers
TRMT6/61A
RNA readers
YTHDF1/2/3
RNA erasers
ALKBH7
Enzymes
PSAT1
RNA types
mRNAs
Modification
ac4C
Label
spacer C18
RNA editing
A to I
Cell Type
CD4⁺ T Cells
Oligonucleotide
2'-OMe, 2'dT (LNP)
RNA Construction
mRNAs-ac4C-TRMT6/61A-YTHDF1/2/3-ALKBH7-PSAT1-spacer C18
Substrates
SAM
Cofactors
ADP
Pathway
Mevalonate pathway
Epigenetic regulator
ARID1A deficiency
Metabolic alteration
Inhibiting reduced glutathione synthesis
Targeting diseases
Adrenocortical carcinoma
RNA-binding proteins
α-synuclein
Metabolic Reprogramming
Mevalonate pathway-α-synuclein-SAM-ADP
Target
TOMM40
Alternative Names
TOMM40; C19orf1; D19S1177E; PER-EC1; PEREC1; TOM40; translocase of outer mitochondrial membrane 40
Format
Liquid
Shipping
All ordered products are shipped from Fedex or UPS.
Handling Advice
Prevent prolonged exposure to light.
Storage
Recommended long-term storage in - 20 ° C, to ensure the longest shelf life of products.
For Research Use Only | Not For Clinical Use
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