TP53-targeted RNA Modification and Metabolomics Analysis Tool

CAT#: ITS-0524-CR62
Cell Type: CD4⁺ T Cells
RNA writers: METTL14
RNA readers: HNRNPs
RNA erasers: ALKBH5
Enzymes: HDACs
RNA types: tRNA
Modification: m1A
RNA editing: A to I
Short Description
This product is a TP53-targeted RNA modification and metabolomics analysis tool based on the m1A (METTL14-HNRNPs-ALKBH5-HDACs-spacer C9) modification and TCA cycle-mediated (hnRNPs-SAM-ADP) metabolic analysis system.
RNA writers
METTL14
RNA readers
HNRNPs
RNA erasers
ALKBH5
Enzymes
HDACs
RNA types
tRNA
Modification
m1A
Label
spacer C9
RNA editing
A to I
Cell Type
CD4⁺ T Cells
Oligonucleotide
2'-OMe (cationic lipoplex)
RNA Construction
tRNA-m1A-METTL14-HNRNPs-ALKBH5-HDACs-spacer C9
Substrates
SAM
Cofactors
ADP
Pathway
TCA cycle
Epigenetic regulator
EZH2 deficiency
Metabolic alteration
Activating branched-chain amino acidsmetabolism
Targeting diseases
Breast Cancer
RNA-binding proteins
hnRNPs
Metabolic Reprogramming
TCA cycle-hnRNPs-SAM-ADP
Target
TP53
Alternative Names
TP53; BCC7; LFS1; P53; TRP53; tumor protein p53; BMFS5; Genes; p53
Gene ID
7157(Human); 22059(Mouse); 24842(Rat)
UniProt ID
O00213(Human)
Format
Liquid
Shipping
All ordered products are shipped from Fedex or UPS.
Handling Advice
Prevent prolonged exposure to light.
Storage
Recommended long-term storage in - 20 ° C, to ensure the longest shelf life of products.
For Research Use Only | Not For Clinical Use
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