TPO-targeted RNA Modification and Metabolomics Analysis Tool

CAT#: ITS-0524-CR180
Cell Type: MDSCs
RNA writers: TRMT61B
RNA readers: YTHDF1/2/3
RNA erasers: ALKBH1
Enzymes: HATs
RNA types: mRNAs
Modification: ψ
RNA editing: A to I
Short Description
This product is a TPO-targeted RNA modification and metabolomics analysis tool based on the ψ (TRMT61B-YTHDF1/2/3-ALKBH1-HATs-phos) modification and Gluconeogenesis-mediated (hnRNPs-SAM-ATP) metabolic analysis system.
RNA writers
TRMT61B
RNA readers
YTHDF1/2/3
RNA erasers
ALKBH1
Enzymes
HATs
RNA types
mRNAs
Modification
ψ
Label
phos
RNA editing
A to I
Cell Type
MDSCs
Oligonucleotide
2'-OMe, 2'dT (LNP)
RNA Construction
mRNAs-ψ-TRMT61B-YTHDF1/2/3-ALKBH1-HATs-phos
Substrates
SAM
Cofactors
ATP
Pathway
Gluconeogenesis
Epigenetic regulator
SMARCA4 overexpression
Metabolic alteration
Upregulating fatty acids synthesis
Targeting diseases
Ovarian Cancers
RNA-binding proteins
hnRNPs
Metabolic Reprogramming
Gluconeogenesis-hnRNPs-SAM-ATP
Target
TPO
Alternative Names
Thyroid peroxidase; thyroperoxidase (TPO
Gene ID
22018(Mouse); 54314(Rat)
UniProt ID
Q62386(Mouse)
Format
Liquid
Shipping
All ordered products are shipped from Fedex or UPS.
Handling Advice
Prevent prolonged exposure to light.
Storage
Recommended long-term storage in - 20 ° C, to ensure the longest shelf life of products.
For Research Use Only | Not For Clinical Use
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