Transaminase-targeted RNA Modification and Metabolomics Analysis Tool

CAT#: ITS-0524-CR259
Cell Type: M2 macrophages
RNA writers: METTL3
RNA readers: YTHDF1
RNA erasers: FTO
Enzymes: ALKBH5
RNA types: mRNAs
Modification: ac4C
RNA editing: A to I
Short Description
This product is a Transaminase-targeted RNA modification and metabolomics analysis tool based on the ac4C (METTL3-YTHDF1-FTO-ALKBH5-Cy7) modification and Glycogen synthesis-mediated (hnRNPs-Succinyl-CoA-α-KG) metabolic analysis system.
RNA writers
METTL3
RNA readers
YTHDF1
RNA erasers
FTO
Enzymes
ALKBH5
RNA types
mRNAs
Modification
ac4C
Label
Cy7
RNA editing
A to I
Cell Type
M2 macrophages
Oligonucleotide
2'-OMe (cationic lipoplex)
RNA Construction
mRNAs-ac4C-METTL3-YTHDF1-FTO-ALKBH5-Cy7
Substrates
Succinyl-CoA
Cofactors
α-KG
Pathway
Glycogen synthesis
Epigenetic regulator
ARID1A deficiency
Metabolic alteration
Inhibiting reduced glutathione synthesis
Targeting diseases
Nasopharyngeal carcinoma
RNA-binding proteins
hnRNPs
Metabolic Reprogramming
Glycogen synthesis-hnRNPs-Succinyl-CoA-α-KG
Target
Transaminase
Alternative Names
Transaminase
Format
Liquid
Shipping
All ordered products are shipped from Fedex or UPS.
Handling Advice
Prevent prolonged exposure to light.
Storage
Recommended long-term storage in - 20 ° C, to ensure the longest shelf life of products.
For Research Use Only | Not For Clinical Use
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