U-251 In Vitro Concentration of Hydrogen Peroxide Assay (Oxidative Stress)

CAT#: ITS-1022-YF4796
Target Cell Organism: Human
Target Cell Name: U-251
Assay Type: Oxidative Stress Assays
Assay Overview
This assay is to provide U-251-based In Vitro Concentration of Hydrogen Peroxide Assay (Oxidative Stress) to accelerate our client's oncology projects. The assay will be customized according to the specific requirements. Please contact our scientists to discuss more details.
Target Cell Name
U-251
Target Cell Organism
Human
Target Cell Background
The U-251 cell line was established at the Wallenberg laboratory, Uppsala, Sweden, almost more than 40 years ago along with several other cell lines derived from human gliomas, and was derived from a male patient with malignant astrocytoma.
Related Diseases
Glioblastoma
Research Area
Oncology
Assay Name
In Vitro Concentration of Hydrogen Peroxide Assay (Oxidative Stress)
Short Description
U-251-cell based In Vitro Concentration of Hydrogen Peroxide Assay (Oxidative Stress)
Assay Type
Oxidative Stress Assays
Assay Type Details
Disturbance between the production of reactive oxygen species (ROS), free radicals and antioxidant mechanisms is defined as the oxidative stress, or more precisely, it is an imbalance between the oxidant and antioxidant state in cells. This imbalance can cause harmful effects to cells and biomolecules, which ultimately causes adverse effects in the whole organism. Oxidative imbalance can target important proteinsand lipids in cells, which can increase the risk of developing a cancer. On the other hand, increased ROS production in cancer cells by certain cancer drugs can also arrest cancer cell cycle and cause senescence and apoptosis through oxidative stress.
Assay Subtype
Markers Thiobarbituric Acid Reactive Substances
For Research Use Only | Not For Clinical Use
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