U87 MG In Vitro Telomere Length Analysis Assay (Senescence)
CAT#: ITS-1022-YF361
Target Cell Organism: Human
Target Cell Alternative Name: U87MG; U-87 MG
Target Cell Name: U87 MG
Assay Type: Cellular Senescence in Cancer Assays
Assay Overview
This assay is to provide U87 MG-based In Vitro Telomere Length Analysis Assay (Senescence) to accelerate our client's oncology projects. The assay will be customized according to the specific requirements. Please contact our scientists to discuss more details.
Target Cell Name
U87 MG
Target Cell Organism
Human
Target Cell Background
U-87 MG is a cell line with epithelial morphology that was isolated from malignant gliomas from a male patient, likely with Glioblastoma. Use these cells in your neuroscience and immuno-oncology research.
Target Cell Alternative Name
U87MG; U-87 MG
Related Diseases
Glioblastoma
Research Area
Oncology
Assay Name
In Vitro Telomere Length Analysis Assay (Senescence)
Short Description
U87 MG-cell based In Vitro Telomere Length Analysis Assay (Senescence)
Assay Description
For the analysis of telomere length, terminal restriction fragment analysis technique has been the commonly used technique for a long time.
Assay Type
Cellular Senescence in Cancer Assays
Assay Type Details
Cell senescence is described as an irreversible physiological event of cell growth arrest, which is known to be caused by alterations of telomeres, oxidative stress, DNA damage and some oncogenes. Inhibition of the program of senescence is one of the main features of tumor cells and it has been reported that cancer cells can be induced to undergo senescence by chemo- and radiotherapies and genetic alterations. Telomeres help to prevent uncontrolled cell proliferation and the absence of telomeres results in aneuploidy and cell death.