UCHL1-targeted RNA Modification and Metabolomics Analysis Tool

CAT#: ITS-0524-CR237
Cell Type: M2 macrophages
RNA writers: METTL3
RNA readers: YTHDF1
RNA erasers: FTO
Enzymes: SIRT1
RNA types: rRNA
Modification: ac4C
RNA editing: C to U
Short Description
This product is a UCHL1-targeted RNA modification and metabolomics analysis tool based on the ac4C (METTL3-YTHDF1-FTO-SIRT1-spacer C9) modification and TCA cycle-mediated (α-synuclein-Acetyl-CoA-ATP) metabolic analysis system.
RNA writers
METTL3
RNA readers
YTHDF1
RNA erasers
FTO
Enzymes
SIRT1
RNA types
rRNA
Modification
ac4C
Label
spacer C9
RNA editing
C to U
Cell Type
M2 macrophages
Oligonucleotide
2'-H
RNA Construction
rRNA-ac4C-METTL3-YTHDF1-FTO-SIRT1-spacer C9
Substrates
Acetyl-CoA
Cofactors
ATP
Pathway
TCA cycle
Epigenetic regulator
SIRT6 deficiency
Metabolic alteration
Upregulating glycolysis
Targeting diseases
Glioma
RNA-binding proteins
α-synuclein
Metabolic Reprogramming
TCA cycle-α-synuclein-Acetyl-CoA-ATP
Target
UCHL1
Alternative Names
UCHL1; HEL-117; NDGOA; PARK5; PGP 9.5; PGP9.5; PGP95; Uch-L1; HEL-S-53; ubiquitin C-terminal hydrolase L1; SPG79; UCHL-1
Format
Liquid
Shipping
All ordered products are shipped from Fedex or UPS.
Handling Advice
Prevent prolonged exposure to light.
Storage
Recommended long-term storage in - 20 ° C, to ensure the longest shelf life of products.
For Research Use Only | Not For Clinical Use
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