VLDL-targeted RNA Modification and Metabolomics Analysis Tool
CAT#: ITS-0524-CR400
Cell Type: M2 macrophages
RNA writers: METTL3
RNA readers: YTHDF1
RNA erasers: FTO
Enzymes: HDACs
RNA types: mRNAs
Modification: m6A
RNA editing: T to C
Short Description
This product is a VLDL-targeted RNA modification and metabolomics analysis tool based on the m6A (METTL3-YTHDF1-FTO-HDACs-spacer C9) modification and Fatty acid catabolism-mediated (MBNL-Lactyl-CoA-NAD+) metabolic analysis system.
RNA writers
METTL3
RNA readers
YTHDF1
RNA erasers
FTO
Enzymes
HDACs
RNA types
mRNAs
Modification
m6A
Label
spacer C9
RNA editing
T to C
Cell Type
M2 macrophages
Oligonucleotide
2'-MOE, GalNAc
RNA Construction
mRNAs-m6A-METTL3-YTHDF1-FTO-HDACs-spacer C9
Substrates
Lactyl-CoA
Cofactors
NAD+
Pathway
Fatty acid catabolism
Epigenetic regulator
ARID1A deficiency
Metabolic alteration
Inhibiting reduced glutathione synthesis
Targeting diseases
Adrenocortical carcinoma
RNA-binding proteins
MBNL
Metabolic Reprogramming
Fatty acid catabolism-MBNL-Lactyl-CoA-NAD+
Target
VLDL
Alternative Names
Very low-density lipoproteins; VLDL
Format
Liquid
Shipping
All ordered products are shipped from Fedex or UPS.
Handling Advice
Prevent prolonged exposure to light.
Storage
Recommended long-term storage in - 20 ° C, to ensure the longest shelf life of products.