Cationic liposomes are used for the delivery of genetic materials such as various types of DNA and RNA. In order to capture more plasmid efficiently, the negative charge of pDNA is neutralized with positive charge of cationic lipids due to electrostatic interaction and deliver them into cells. So they are researched for use as delivery vectors in gene therapy.
Lipid Composition
DDAB Chol
Applications
Cancer research; Target delivery
Format
Liquid
Hydration Solution
Deionized RNAse-free Water
External Solution
Deionized RNAse-free Water
Storage
2°C - 8°C in dark (do not freeze)
Size
100 nm
Shelf Life
6 months
Quantity
5mL (available in lyophilized powder)
Dosage
Download
DataSheet
MSDS
FAQs Customer ReviewsRelated Sections
What is the composition of DDAB:Chol liposomes?
DDAB:Chol liposomes are composed of a 1:1 ratio of dimethyldioctadecylammonium bromide (DDAB) and cholesterol (Chol). This formulation ensures stability and efficient encapsulation of various cargo molecules for research purposes.
How are DDAB:Chol liposomes prepared?
DDAB:Chol liposomes are typically prepared by thin-film hydration method followed by sonication or extrusion. This process ensures uniform size distribution and lipid bilayer integrity, crucial for reliable experimental outcomes.
What are the advantages of using DDAB:Chol liposomes?
DDAB:Chol liposomes offer several advantages, including high encapsulation efficiency, enhanced stability, and controlled release characteristics. Moreover, their cationic nature facilitates interactions with negatively charged biomolecules, aiding in targeted delivery applications.
How can DDAB:Chol liposomes be utilized in research?
DDAB:Chol liposomes find applications in various research areas such as drug delivery, gene therapy, and vaccine development. Researchers can use them to encapsulate and deliver therapeutic agents, nucleic acids, or imaging agents with precision and efficacy.
Are there any considerations for handling DDAB:Chol liposomes?
Due to their cationic nature, DDAB:Chol liposomes should be handled with caution to avoid electrostatic interactions with surfaces or biomolecules. Additionally, proper storage conditions, such as refrigeration or freeze-drying, are recommended to maintain their stability.
Enhanced Stability and Biocompatibility
Creative Biolabs' DDAB:Chol liposomes offer exceptional stability and biocompatibility, crucial for our drug formulation studies. Their consistent performance surpasses other options, ensuring reliable results in our research.
Superior Encapsulation Efficiency
We've experienced unparalleled drug encapsulation efficiency with Creative Biolabs' DDAB:Chol liposomes. Their advanced formulation enables maximum drug loading, enhancing the effectiveness of our experimental therapies.
Optimized Drug Delivery Kinetics
Creative Biolabs' DDAB:Chol liposomes excel in delivering drugs with precise kinetics, a critical factor in our research on controlled drug release. Their reliable performance significantly advances our drug development efforts.
Seamless Integration in Research Protocols
The liposomes seamlessly integrate into our research protocols, streamlining our drug development process. Their versatility and reliability make them an indispensable tool in our studies.
Dedicated Customer Support
We appreciate the dedicated support provided by Creative Biolabs for their DDAB:Chol liposomes. Their responsive team ensures smooth experimentation and prompt resolution of any issues, enhancing our research productivity.
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