Mannosylated Fluorescent Liposome DiR (CLBD007LYm)

Mannose receptor targeting by mannosylated liposomes has been demonstrated for a variety of mannosylated lipid conjugates in a variety of liposome morphologies and compositions in several different models. Mannosylated Fluorescent Liposome DiR incorporates a lipophilic dye inside its membrane, which is insoluble in water. Its fluorescence is easily detected when incorporated into membranes. DiR covers a wide range of excitation and emission wavelengths from 300s to 900s. DiR belongs to the dialkylcarbocyanines family of compounds. They have extremely high extinction coefficients, moderate fluorescence quantum yields and short excited state lifetimes in lipid environments (~1 ns).
Product Name
Mannosylated Fluorescent Liposome DiR
Cat
CLBD007LYm
Description
Mannose receptor targeting by mannosylated liposomes has been demonstrated for a variety of mannosylated lipid conjugates in a variety of liposome morphologies and compositions in several different models. Mannosylated Fluorescent Liposome DiR incorporates a lipophilic dye inside its membrane, which is insoluble in water. Its fluorescence is easily detected when incorporated into membranes. DiR covers a wide range of excitation and emission wavelengths from 300s to 900s. DiR belongs to the dialkylcarbocyanines family of compounds. They have extremely high extinction coefficients, moderate fluorescence quantum yields and short excited state lifetimes in lipid environments (~1 ns).
Lipid Composition
L-alpha-Phosphatidylcholine, Cholesterol
Fluorescent Dye
1,1'-Dioctadecyl-3,3,3',3'-Tetramethylindotricarbocyanine Iodide (DiR)
Mannosylation
4-Aminophenyl-alpha-D-mannopyranoside
Concentration
0.066 mg/mL
Buffer
PBS, pH 7.4
Storage
Store in dark at +4°C and do not freeze
Size
1.5-2 µm
Quantity
2, 5, 10, 20, 25 mL
For research use only. Not intended for any clinical use.

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