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Magic™ Antibody Discovery - Cynomolgus Fc gamma RIIB/CD32b (46-224) Membrane Protein, Partial, -His -Avi tag, [Biotin] (CAT#: MP1415F)

Datasheet
This membrane protein is Cynomolgus Fc gamma RIIB/CD32b (46-224). It has been tested in SDS-PAGE, SPR, BLI. We provide this protein to facilitate your membrane protein antibody discovery and development.

Product Specifications

  • Host Species
  • Cynomolgus
  • Target Protein
  • Fc gamma RIIB/CD32b
  • Protein Length
  • ECD
  • Molecular Weight
  • The protein has a calculated MW of 23.6 kDa. The protein migrates as 30-35 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
  • Sequence
  • AA Ala 46 - Pro 224 (Accession # Q8SPW3-1).

Product Description

  • Activity
  • Yes
  • Application
  • SDS-PAGE, SPR, BLI
  • Expression Systems
  • HEK293
  • Tag
  • His tag at the C-terminus followed by an Avi tag
  • Protein Format
  • Soluble
  • Reconstitution
  • Please see Certificate of Analysis for specific instructions.
  • Endotoxin
  • <1.0 EU/μg by the LAL method
  • Purity
  • >95% as determined by SDS-PAGE
  • Buffer
  • Lyophilized from 0.22 μm filtered solution in PBS, pH7.4. Normally trehalose is added as protectant before lyophilization.

Target

  • Target Protein
  • Fc gamma RIIB/CD32b
  • Full Name
  • Fc fragment of IgG receptor IIb
  • Introduction
  • The protein encoded by this gene is a low affinity receptor for the Fc region of immunoglobulin gamma complexes. The encoded protein is involved in the phagocytosis of immune complexes and in the regulation of antibody production by B-cells. Variations in this gene may increase susceptibilty to systemic lupus erythematosus (SLE). Several transcript variants encoding different isoforms have been found for this gene.
  • Alternative Names
  • CD32, FCG2, CD32B, FCGR2, IGFR2, FCGR2C, FcRII-c, low affinity immunoglobulin gamma Fc region receptor II-b, CDw32, Fc fragment of IgG, low affinity II, receptor for (CD32), Fc fragment of IgG, low affinity IIb, receptor (CD32), Fc fragment of IgG, low affinity IIb, receptor for (CD32), Fc gamma RIIb, Fc gamma receptor IIb, Fc-gamma RII-c, Fc-gamma-RIIc, IgG Fc receptor II-c, Low affinity immunoglobulin gamma Fc region receptor II-c, fc-gamma RII-b, fc-gamma-RIIb, fcRII-b, igG Fc receptor II-b

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