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Magic™ Antibody Discovery - Cynomolgus / Rhesus macaque B7-1 / CD80 (35-242) Membrane Protein, Partial, -His tag (CAT#: MP0957F)

Datasheet
This membrane protein is Cynomolgus / Rhesus macaque B7-1 / CD80 (38-245). It has been tested in SDS-PAGE, ELISA, HPLC. We provide this protein to facilitate your membrane protein antibody discovery and development.

Product Specifications

  • Host Species
  • Cynomolgus / Rhesus macaque
  • Target Protein
  • B7-1 / CD80
  • Protein Length
  • ECD
  • Molecular Weight
  • The protein has a calculated MW of 25.8 kDa. The protein migrates as 43-55 kDa under reducing (R) condition (SDS-PAGE) due to different glycosylation.
  • Sequence
  • AA Val 35 - Asn 242 (Accession # G7NXN7).

Product Description

  • Activity
  • Yes
  • Application
  • SDS-PAGE, ELISA, HPLC
  • Expression Systems
  • HEK293
  • Tag
  • His tag at the C-terminus
  • Protein Format
  • Soluble
  • Reconstitution
  • Please see Certificate of Analysis for specific instructions.
  • Endotoxin
  • <1.0 EU/μg by the LAL method
  • Purity
  • >95% as determined by SDS-PAGE.
    >90% as determined by SEC-HPLC.
  • Buffer
  • Lyophilized from 0.22 μm filtered solution in PBS, pH7.4. Normally trehalose is added as protectant before lyophilization.

Target

  • Target Protein
  • B7-1 / CD80
  • Full Name
  • CD80 molecule
  • Introduction
  • The protein encoded by this gene is a membrane receptor that is activated by the binding of CD28 or CTLA-4. The activated protein induces T-cell proliferation and cytokine production. This protein can act as a receptor for adenovirus subgroup B and may play a role in lupus neuropathy.
  • Alternative Names
  • T-lymphocyte activation antigen CD80, B-lymphocyte activation antigen B7, CD80 antigen (CD28 antigen ligand 1, B7-1 antigen), CTLA-4 counter-receptor B7.1, activation B7-1 antigen, costimulatory factor CD80, costimulatory molecule variant IgV-CD80

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