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Magic™ Antibody Discovery - Cynomolgus TRAIL R2 / DR5 / TNFRSF10B (58-212) Membrane Protein, Partial, -His tag (CAT#: MP0458F)

This membrane protein is Cynomolgus TRAIL R2 / DR5 / TNFRSF10B (58-212). It has been tested in SDS-PAGE. We provide this protein to facilitate your membrane protein antibody discovery and development.

Product Specifications

  • Host Species
  • Cynomolgus
  • Target Protein
  • TRAIL R2 / DR5 / TNFRSF10B
  • Protein Length
  • ECD
  • Molecular Weight
  • The protein has a calculated MW of 19.1 kDa.
  • Sequence
  • AA Ile 58 - Ser 212 (Accession # A0A2K5TXK0-1).

Product Description

  • Application
  • SDS-PAGE
  • Expression Systems
  • HEK293
  • Tag
  • His tag at the C-terminus
  • Protein Format
  • Soluble
  • Reconstitution
  • Please see Certificate of Analysis for specific instructions.
  • Buffer
  • Please contact us for detailed information.

Target

  • Target Protein
  • TRAIL R2 / DR5 / TNFRSF10B
  • Full Name
  • TNF receptor superfamily member 10b
  • Introduction
  • The protein encoded by this gene is a member of the TNF-receptor superfamily, and contains an intracellular death domain. This receptor can be activated by tumor necrosis factor-related apoptosis inducing ligand (TNFSF10/TRAIL/APO-2L), and transduces an apoptosis signal. Studies with FADD-deficient mice suggested that FADD, a death domain containing adaptor protein, is required for the apoptosis mediated by this protein. Two transcript variants encoding different isoforms and one non-coding transcript have been found for this gene.
  • Alternative Names
  • TNFRSF10B, TRAILR2, TRAIL-R2, CD262, DR5, KILLER, TRICK2, ZTNFR9, TRICKB

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