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Magic™ Antibody Discovery - Human Activin A / INHBA (.) Membrane Protein, Partial, His- tag (CAT#: MP0937F)

Datasheet
This membrane protein is Human Activin A / INHBA (311-426). It has been tested in SDS-PAGE, Cell based assay. We provide this protein to facilitate your membrane protein antibody discovery and development.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • Activin A / INHBA
  • Protein Length
  • ECD
  • Molecular Weight
  • The protein has a calculated MW of 13.0 kDa (mature) and 32.0 kDa (pro). As a result of glycosylation and Interchain disulfide bond, the protein migrates as 15 kDa (mature) and 43-48 kDa (pro) under reducing (R) condition, and 27 kDa (mature), 43-48 kDa (pro) and 60 kDa (pro & mature) under non-reducing (NR) condition (SDS-PAGE).
  • Sequence
  • Ser 21 - Ser 426 (Accession # AAH07858.1).

Product Description

  • Activity
  • Yes
  • Application
  • SDS-PAGE, Cell based assay
  • Expression Systems
  • HEK293
  • Tag
  • His tag at the N-terminus
  • Protein Format
  • Soluble
  • Reconstitution
  • Please see Certificate of Analysis for specific instructions.
  • Endotoxin
  • <1.0 EU/μg by the LAL method
  • Purity
  • >95% as determined by SDS-PAGE.
  • Buffer
  • Lyophilized from 0.22 μm filtered solution in PBS, pH7.4. Normally trehalose is added as protectant before lyophilization.

Target

  • Target Protein
  • Activin A / INHBA
  • Full Name
  • inhibin subunit beta A
  • Introduction
  • This gene encodes a member of the TGF-beta (transforming growth factor-beta) superfamily of proteins. The encoded preproprotein is proteolytically processed to generate a subunit of the dimeric activin and inhibin protein complexes. These complexes activate and inhibit, respectively, follicle stimulating hormone secretion from the pituitary gland. The encoded protein also plays a role in eye, tooth and testis development. Elevated expression of this gene may be associated with cancer cachexia in human patients.
  • Alternative Names
  • EDF; FRP; inhibin beta A chain; FSH-releasing protein; Inhibin, beta-1; activin beta-A chain; erythroid differentiation factor; erythroid differentiation protein; follicle-stimulating hormone-releasing protein; inhibin beta A subunit; inhibin, beta A (activin A, activin AB alpha polypeptide)

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