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Magic™ Antibody Discovery - Human Alpha-Synuclein (1-140) Membrane Protein, Partial, -His tag (CAT#: MP0919F)

Datasheet
This membrane protein is Human Alpha-Synuclein (28-526). It has been tested in SDS-PAGE. We provide this protein to facilitate your membrane protein antibody discovery and development.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • Alpha-Synuclein
  • Protein Length
  • ECD
  • Molecular Weight
  • The protein has a calculated MW of 16.3 kDa. The protein migrates as 19 kDa under reducing (R) condition (SDS-PAGE).
  • Sequence
  • AA Met 1 - Ala 140 (Accession # P37840-1).

Product Description

  • Application
  • SDS-PAGE
  • Expression Systems
  • E.coli
  • Tag
  • His tag at the C-terminus
  • Protein Format
  • Soluble
  • Reconstitution
  • Please see Certificate of Analysis for specific instructions.
  • Endotoxin
  • <1.0 EU/μg by the LAL method
  • Purity
  • >90% as determined by SDS-PAGE.
  • Buffer
  • Lyophilized from 0.22 μm filtered solution in 100 mM NaAC, pH7.0. Normally trehalose is added as protectant before lyophilization.

Target

  • Target Protein
  • Alpha-Synuclein
  • Full Name
  • synuclein alpha
  • Introduction
  • Alpha-synuclein is a member of the synuclein family, which also includes beta- and gamma-synuclein. Synucleins are abundantly expressed in the brain and alpha- and beta-synuclein inhibit phospholipase D2 selectively. SNCA may serve to integrate presynaptic signaling and membrane trafficking. Defects in SNCA have been implicated in the pathogenesis of Parkinson disease. SNCA peptides are a major component of amyloid plaques in the brains of patients with Alzheimer's disease. Alternatively spliced transcripts encoding different isoforms have been identified for this gene.
  • Alternative Names
  • PD1; NACP; PARK1; PARK4; alpha-synuclein; I+/--synuclein; non A-beta component of AD amyloid; synuclein alpha-140; synuclein, alpha (non A4 component of amyloid precursor); truncated alpha synuclein

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