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Magic™ Antibody Discovery - Human ANGPTL7 / CDT6 (27-346) Membrane Protein, Partial, -mIgG1 Fc -Avi tag, [Biotin] (CAT#: MP0939F)

This membrane protein is Human ANGPTL7 / CDT6 (17-497). It has been tested in SDS-PAGE, ELISA. We provide this protein to facilitate your membrane protein antibody discovery and development.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • ANGPTL7 / CDT6
  • Protein Length
  • ECD
  • Molecular Weight
  • The protein has a calculated MW of 65.8 kDa. The protein migrates as 66 kDa and 75-95 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
  • Sequence
  • AA Gln 27 - Pro 346 (Accession # O43827-1).

Product Description

  • Activity
  • Yes
  • Application
  • SDS-PAGE, ELISA
  • Expression Systems
  • HEK293
  • Tag
  • Mouse IgG2a Fc tag at the C-terminus, followed by an Avi tag
  • Protein Format
  • Soluble
  • Reconstitution
  • Please see Certificate of Analysis for specific instructions.
  • Endotoxin
  • <1.0 EU/μg by the LAL method
  • Conjugation
  • Biotin
  • Purity
  • >90% as determined by SDS-PAGE.
  • Buffer
  • Lyophilized from 0.22 μm filtered solution in Tris with Glycine, Arginine and NaCl, pH7.5. Normally trehalose is added as protectant before lyophilization.

Target

  • Target Protein
  • ANGPTL7 / CDT6
  • Full Name
  • angiopoietin like 7
  • Introduction
  • Has a role in the formation and organization of the extracellular matrix. In the eye, it functions as a mediator of dexamethasone-induced matrix deposition in the trabecular meshwork, the tissue responsible for the outflow of the ocular aqueous humor and for the maintenance of intraocular pressure (PubMed:21199193). Is a negative regulator of angiogenesis in the cornea, and plays a major role in maintaining corneal avascularity and transparency (PubMed:25622036).
  • Alternative Names
  • AngX; CDT6; dJ647M16.1; angiopoietin-related protein 7; angiopoietin-like factor (CDT6); angiopoietin-like protein 7; cornea-derived transcript 6 protein

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