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Magic™ Antibody Discovery - Human Apolipoprotein E / APOE (19-317) Membrane Protein, Partial, His- tag (CAT#: MP0916F)

This membrane protein is Human Apolipoprotein E / APOE (2-312). It has been tested in SDS-PAGE. We provide this protein to facilitate your membrane protein antibody discovery and development.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • Apolipoprotein E / APOE
  • Protein Length
  • ECD
  • Molecular Weight
  • The protein has a calculated MW of 36.1 kDa.
  • Sequence
  • AA Lys 19 - His 317 (Accession # P02649-1).

Product Description

  • Application
  • SDS-PAGE
  • Expression Systems
  • HEK293
  • Tag
  • His tag at the N-terminus
  • Protein Format
  • Soluble
  • Reconstitution
  • Please see Certificate of Analysis for specific instructions.
  • Buffer
  • Lyophilized from 0.22 μm filtered solution in PBS, pH7.4. Normally trehalose is added as protectant before lyophilization.

Target

  • Target Protein
  • Apolipoprotein E / APOE
  • Full Name
  • apolipoprotein E
  • Introduction
  • The protein encoded by this gene is a major apoprotein of the chylomicron. It binds to a specific liver and peripheral cell receptor, and is essential for the normal catabolism of triglyceride-rich lipoprotein constituents. This gene maps to chromosome 19 in a cluster with the related apolipoprotein C1 and C2 genes. Mutations in this gene result in familial dysbetalipoproteinemia, or type III hyperlipoproteinemia (HLP III), in which increased plasma cholesterol and triglycerides are the consequence of impaired clearance of chylomicron and VLDL remnants.
  • Alternative Names
  • AD2; LPG; APO-E; ApoE4; LDLCQ5; apolipoprotein E; apolipoprotein E3

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