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Magic™ Antibody Discovery - Human CD200 R1 / CRTR2 (27-266) Membrane Protein, Partial, -hIgG1 Fc -Avi tag, [Biotin] (CAT#: MP1178F)

Datasheet
This membrane protein is Human CD200 R1 / CRTR2 (27-266). It has been tested in SDS-PAGE, ELISA. We provide this protein to facilitate your membrane protein antibody discovery and development.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • CD200 R1 / CRTR2
  • Protein Length
  • ECD
  • Molecular Weight
  • The protein has a calculated MW of 55.8 kDa. The protein migrates as 70-115 KDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
  • Sequence
  • AA Ala 27 - Leu 266 (Accession # AAQ19772.1).

Product Description

  • Activity
  • Yes
  • Application
  • SDS-PAGE, ELISA
  • Expression Systems
  • HEK293
  • Tag
  • Human IgG1 Fc tag at the C-terminus, followed by a Avi tag
  • Protein Format
  • Soluble
  • Reconstitution
  • Please see Certificate of Analysis for specific instructions.
  • Endotoxin
  • <1.0 EU/μg by the LAL method
  • Conjugation
  • Biotin
  • Purity
  • >95% as determined by SDS-PAGE.
  • Buffer
  • Lyophilized from 0.22 μm filtered solution in Tris with Glycine, Arginine and NaCl, pH7.5. Normally trehalose is added as protectant before lyophilization.

Target

  • Target Protein
  • CD200 R1 / CRTR2
  • Full Name
  • CD200 receptor 1
  • Introduction
  • This gene encodes a receptor for the OX-2 membrane glycoprotein. Both the receptor and substrate are cell surface glycoproteins containing two immunoglobulin-like domains. This receptor is restricted to the surfaces of myeloid lineage cells and the receptor-substrate interaction may function as a myeloid downregulatory signal. Mouse studies of a related gene suggest that this interaction may control myeloid function in a tissue-specific manner. Alternative splicing of this gene results in multiple transcript variants.
  • Alternative Names
  • cell surface glycoprotein CD200 receptor 1, CD200 cell surface glycoprotein receptor, MOX2 receptor, cell surface glycoprotein OX2 receptor 1, cell surface glycoprotein receptor CD200

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