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Magic™ Antibody Discovery - Human Dkk-3 (22-350) Membrane Protein, Partial, -His tag (CAT#: MP1351F)

Datasheet
This membrane protein is Human Dkk-3 (22-350). It has been tested in SDS-PAGE. We provide this protein to facilitate your membrane protein antibody discovery and development.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • Dkk-3
  • Protein Length
  • ECD
  • Molecular Weight
  • The protein has a calculated MW of 37.0 kDa. The protein migrates as 45-65 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
  • Sequence
  • AA Ala 22 - Ile 350 (Accession # Q9UBP4-1(R335G)).

Product Description

  • Application
  • SDS-PAGE
  • Expression Systems
  • HEK293
  • Tag
  • His tag at the C-terminus
  • Protein Format
  • Soluble
  • Reconstitution
  • Please see Certificate of Analysis for specific instructions.
  • Endotoxin
  • <1.0 EU/μg by the LAL method
  • Purity
  • >95% as determined by SDS-PAGE.
  • Buffer
  • Lyophilized from 0.22 μm filtered solution in PBS, pH7.4. Normally trehalose is added as protectant before lyophilization.

Target

  • Target Protein
  • Dkk-3
  • Full Name
  • dickkopf WNT signaling pathway inhibitor 3
  • Introduction
  • This gene encodes a protein that is a member of the dickkopf family. The secreted protein contains two cysteine rich regions and is involved in embryonic development through its interactions with the Wnt signaling pathway. The expression of this gene is decreased in a variety of cancer cell lines and it may function as a tumor suppressor gene. Alternative splicing results in multiple transcript variants encoding the same protein.
  • Alternative Names
  • dkk-3; C87148; mDkk-3; AW061014; dickkopf-related protein 3; dickkopf homolog 3; dickkopf-3

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