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Magic™ Antibody Discovery - Human Fc epsilon RI alpha (26-204) Membrane Protein, Partial, -hIgG1 Fc tag (CAT#: MP0108F)

Datasheet
This membrane protein is Human Fc epsilon RI alpha (26-204). It has been tested in SDS-PAGE, BLI. We provide this protein to facilitate your membrane protein antibody discovery and development.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • Fc epsilon RI alpha
  • Protein Length
  • ECD
  • Molecular Weight
  • The protein has a calculated MW of 47.3 kDa. The protein migrates as 55-85 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
  • Sequence
  • AA Val 26 - Leu 204 (Accession # P12319-1).

Product Description

  • Activity
  • Yes
  • Application
  • SDS-PAGE, BLI
  • Expression Systems
  • HEK293
  • Tag
  • Human IgG1 Fc tag at the C-terminus
  • Protein Format
  • Soluble
  • Reconstitution
  • Please see Certificate of Analysis for specific instructions.
  • Endotoxin
  • <1.0 EU/μg by the LAL method
  • Purity
  • >95% as determined by SDS-PAGE.
  • Buffer
  • Lyophilized from 0.22 μm filtered solution in Tris with Glycine, Arginine and NaCl, pH7.5. Normally trehalose is added as protectant before lyophilization.

Target

  • Target Protein
  • Fc epsilon RI alpha
  • Full Name
  • Fc fragment of IgE receptor Ia
  • Introduction
  • The immunoglobulin epsilon receptor (IgE receptor) is the initiator of the allergic response. When two or more high-affinity IgE receptors are brought together by allergen-bound IgE molecules, mediators such as histamine that are responsible for allergy symptoms are released. This receptor is comprised of an alpha subunit, a beta subunit, and two gamma subunits. The protein encoded by this gene represents the alpha subunit.
  • Alternative Names
  • FCE1A; FcERI; high affinity immunoglobulin epsilon receptor subunit alpha; Fc IgE receptor, alpha polypeptide; Fc epsilon RI alpha-chain; Fc epsilon receptor Ia; Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide; Fc-epsilon RI-alpha; high affinity immunoglobulin epsilon receptor alpha-subunit; igE Fc receptor subunit alpha; immunoglobulin E receptor, high-affinity, of mast cells, alpha polypeptide

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