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Magic™ Antibody Discovery - Human Fc gamma RIIB/CD32b (46-217) Membrane Protein, Partial, -Avi -His tag, [Biotin] (CAT#: MP1417F)

Datasheet
This membrane protein is Human Fc gamma RIIB/CD32b (46-217). It has been tested in SDS-PAGE, SPR, BLI. We provide this protein to facilitate your membrane protein antibody discovery and development.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • Fc gamma RIIB/CD32b
  • Protein Length
  • ECD
  • Molecular Weight
  • The protein has a calculated MW of 23.0 kDa. The protein migrates as 25 kDa and 30-35 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
  • Sequence
  • AA Ala 46 - Pro 217 (Accession # P31994-1).

Product Description

  • Activity
  • Yes
  • Application
  • SDS-PAGE, SPR, BLI
  • Expression Systems
  • HEK293
  • Tag
  • Avi tag at the C-terminus, followed by a His tag.
  • Protein Format
  • Soluble
  • Reconstitution
  • Please see Certificate of Analysis for specific instructions.
  • Endotoxin
  • <1.0 EU/μg by the LAL method
  • Purity
  • >95% as determined by SDS-PAGE
  • Buffer
  • Lyophilized from 0.22 μm filtered solution in PBS, pH7.4. Normally trehalose is added as protectant before lyophilization.

Target

  • Target Protein
  • Fc gamma RIIB/CD32b
  • Full Name
  • Fc fragment of IgG receptor IIb
  • Introduction
  • The protein encoded by this gene is a low affinity receptor for the Fc region of immunoglobulin gamma complexes. The encoded protein is involved in the phagocytosis of immune complexes and in the regulation of antibody production by B-cells. Variations in this gene may increase susceptibilty to systemic lupus erythematosus (SLE). Several transcript variants encoding different isoforms have been found for this gene.
  • Alternative Names
  • CD32; FCG2; CD32B; FCGR2; IGFR2; FCGR2C; FcRII-c; low affinity immunoglobulin gamma Fc region receptor II-b; CDw32; Fc fragment of IgG, low affinity II, receptor for (CD32); Fc fragment of IgG, low affinity IIb, receptor (CD32); Fc fragment of IgG, low affinity IIb, receptor for (CD32); Fc gamma RIIb; Fc gamma receptor IIb; Fc-gamma RII-c; Fc-gamma-RIIc; IgG Fc receptor II-c; Low affinity immunoglobulin gamma Fc region receptor II-c; fc-gamma RII-b; fc-gamma-RIIb; fcRII-b; igG Fc receptor II-b

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