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This membrane protein is Human Flt3 ligand (27-185). It has been tested in SDS-PAGE, ELISA. We provide this protein to facilitate your membrane protein antibody discovery and development.
Product Specifications
Host Species
Human
Target Protein
Flt3 ligand
Protein Length
ECD
Molecular Weight
The protein has a calculated MW of 18.0 kDa. The protein migrates as 25-30 kDa under reducing (R) condition (SDS-PAGE).
Sequence
AA Thr 27 - Pro 185 (Accession # AAI26294).
Product Description
Activity
Yes
Application
SDS-PAGE, ELISA
Expression Systems
HEK293
Tag
No tag
Protein Format
Soluble
Reconstitution
Please see Certificate of Analysis for specific instructions.
Endotoxin
<1.0 EU/μg by the LAL method
Purity
>95% as determined by SDS-PAGE.
Buffer
Lyophilized from 0.22 μm filtered solution in PBS, pH7.4. Normally trehalose is added as protectant before lyophilization.
Target
Target Protein
Flt3 ligand
Full Name
fms related receptor tyrosine kinase 3 ligand
Introduction
Dendritic cells (DCs) provide the key link between innate and adaptive immunity by recognizing pathogens and priming pathogen-specific immune responses. FLT3LG controls the development of DCs and is particularly important for plasmacytoid DCs and CD8 (see MIM 186910)-positive classical DCs and their CD103 (ITGAE; MIM 604682)-positive tissue counterparts