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Magic™ Antibody Discovery - Human ICOS / CD278 (21-141) Membrane Protein, Partial, -hIgG1 Fc tag (CAT#: MP0858F)

Datasheet
This membrane protein is Human ICOS / CD278 (21-144(C137S,C138S)). It has been tested in SDS-PAGE, ELISA. We provide this protein to facilitate your membrane protein antibody discovery and development.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • ICOS / CD278
  • Protein Length
  • ECD
  • Molecular Weight
  • The protein has a calculated MW of 40.2 kDa. The protein migrates as 46-55 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
  • Sequence
  • AA Glu 21 - Phe 141 (Accession # Q9Y6W8-1).

Product Description

  • Activity
  • Yes
  • Application
  • SDS-PAGE, ELISA
  • Expression Systems
  • HEK293
  • Tag
  • Human IgG1 Fc tag at the C-terminus
  • Protein Format
  • Soluble
  • Reconstitution
  • Please see Certificate of Analysis for specific instructions.
  • Endotoxin
  • <1.0 EU/μg by the LAL method
  • Purity
  • >95% as determined by SDS-PAGE.
  • Buffer
  • Lyophilized from 0.22 μm filtered solution in Tris with Glycine, Arginine and NaCl, pH7.5. Normally trehalose is added as protectant before lyophilization.

Target

  • Target Protein
  • ICOS / CD278
  • Full Name
  • inducible T cell costimulator
  • Introduction
  • The protein encoded by this gene belongs to the CD28 and CTLA-4 cell-surface receptor family. It forms homodimers and plays an important role in cell-cell signaling, immune responses, and regulation of cell proliferation.
  • Alternative Names
  • AILIM; CD278; CVID1; inducible T-cell costimulator; activation-inducible lymphocyte immunomediatory molecule; inducible T-cell co-stimulator; inducible costimulator

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