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Magic™ Antibody Discovery - Human IGFBP-3 (28-291) Membrane Protein, Partial, -His tag (CAT#: MP0252F)

Datasheet
This membrane protein is Human IGFBP-3 (28-291). It has been tested in SDS-PAGE, ELISA. We provide this protein to facilitate your membrane protein antibody discovery and development.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • IGFBP-3
  • Protein Length
  • ECD
  • Molecular Weight
  • The protein has a calculated MW of 29.6 kDa. The protein migrates as 40-50 kDa under reducing (R) condition (SDS-PAGE).
  • Sequence
  • AA Gly 28 - Lys 291 (Accession # AAH18962).

Product Description

  • Activity
  • Yes
  • Application
  • SDS-PAGE, ELISA
  • Expression Systems
  • HEK293
  • Tag
  • His tag at the C-terminus
  • Protein Format
  • Soluble
  • Reconstitution
  • Please see Certificate of Analysis for specific instructions.
  • Endotoxin
  • <1.0 EU/μg by the LAL method
  • Purity
  • >95% as determined by SDS-PAGE.
  • Buffer
  • Lyophilized from 0.22 μm filtered solution in PBS, pH7.4. Normally trehalose is added as protectant before lyophilization.

Target

  • Target Protein
  • IGFBP-3
  • Full Name
  • insulin like growth factor binding protein 3
  • Introduction
  • This gene is a member of the insulin-like growth factor binding protein (IGFBP) family and encodes a protein with an IGFBP domain and a thyroglobulin type-I domain. The protein forms a ternary complex with insulin-like growth factor acid-labile subunit (IGFALS) and either insulin-like growth factor (IGF) I or II. In this form, it circulates in the plasma, prolonging the half-life of IGFs and altering their interaction with cell surface receptors. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
  • Alternative Names
  • IBP3; BP-53; insulin-like growth factor-binding protein 3; IBP-3; IGF-binding protein 3; IGFBP-3; acid stable subunit of the 140 K IGF complex; binding protein 29; binding protein 53; growth hormone-dependent binding protein

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