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Magic™ Antibody Discovery - Human IL-17E / IL-25 (33-177) Membrane Protein, Partial, -His tag (CAT#: MP0381F)

Datasheet
This membrane protein is Human IL-17E / IL-25 (33-177). It has been tested in SDS-PAGE. We provide this protein to facilitate your membrane protein antibody discovery and development.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • IL-17E / IL-25
  • Protein Length
  • ECD
  • Molecular Weight
  • The protein has a calculated MW of 17.6 kDa. The protein migrates as 23-28 kDa under reducing (R) condition (SDS-PAGE) due to different glycosylation.
  • Sequence
  • AA Tyr 33 - Gly 177 (Accession # NP_073626.1).

Product Description

  • Application
  • SDS-PAGE
  • Expression Systems
  • HEK293
  • Tag
  • His tag at the C-terminus
  • Protein Format
  • Soluble
  • Reconstitution
  • Please see Certificate of Analysis for specific instructions.
  • Endotoxin
  • <1.0 EU/μg by the LAL method
  • Purity
  • >95% as determined by SDS-PAGE.
  • Buffer
  • Lyophilized from 0.22 μm filtered solution in PBS, pH7.4. Normally trehalose is added as protectant before lyophilization.

Target

  • Target Protein
  • IL-17E / IL-25
  • Full Name
  • interleukin 25
  • Introduction
  • The protein encoded by this gene is a cytokine that shares sequence similarity with interleukin 17. This cytokine can induce NF-kappaB activation, and stimulate the production of interleukin 8. Both this cytokine and interleukin 17B are ligands for the cytokine receptor IL17BR. Studies of a similar gene in mice suggest that this cytokine may be a pro-inflammatory cytokine favoring the Th2-type immune response. Alternative splicing results in multiple transcript variants.
  • Alternative Names
  • IL-17E, IL-25, Interleukin-25

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