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Magic™ Antibody Discovery - Human IL-18 R1 / CD218a (19-329) Membrane Protein, Partial, -hIgG1 Fc tag (CAT#: MP0362F)

Datasheet
This membrane protein is Human IL-18 R1 / CD218a (19-329). It has been tested in SDS-PAGE. We provide this protein to facilitate your membrane protein antibody discovery and development.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • IL-18 R1 / CD218a
  • Protein Length
  • ECD
  • Molecular Weight
  • The protein has a calculated MW of 62.4 kDa. The protein migrates as 90-110 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
  • Sequence
  • AA Ala 19 - Arg 329 (Accession # AAH69575).

Product Description

  • Application
  • SDS-PAGE
  • Expression Systems
  • HEK293
  • Tag
  • Human IgG1 Fc tag at the C-terminus
  • Protein Format
  • Soluble
  • Reconstitution
  • Please see Certificate of Analysis for specific instructions.
  • Endotoxin
  • <1.0 EU/μg by the LAL method
  • Purity
  • >95% as determined by SDS-PAGE.
  • Buffer
  • Lyophilized from 0.22 μm filtered solution in Tris with Glycine, Arginine and NaCl, pH7.5. Normally trehalose is added as protectant before lyophilization.

Target

  • Target Protein
  • IL-18 R1 / CD218a
  • Full Name
  • interleukin 18 receptor 1
  • Introduction
  • The protein encoded by this gene is a cytokine receptor that belongs to the interleukin 1 receptor family. This receptor specifically binds interleukin 18 (IL18), and is essential for IL18 mediated signal transduction. IFN-alpha and IL12 are reported to induce the expression of this receptor in NK and T cells. This gene along with four other members of the interleukin 1 receptor family, including IL1R2, IL1R1, ILRL2 (IL-1Rrp2), and IL1RL1 (T1/ST2), form a gene cluster on chromosome 2q. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
  • Alternative Names
  • CD218a; IL18RA; IL1RRP; CDw218a; IL-1Rrp; IL-18Ralpha; IL18Ralpha2; IL-18R-alpha; interleukin-18 receptor 1; CD218 antigen-like family member A; IL1 receptor-related protein; cytokine receptor; interleukin-18 receptor alpha

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