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Magic™ Antibody Discovery - Human IL-7 R alpha / CD127 (21-236) Membrane Protein, Partial, -mIgG2a Fc tag (CAT#: MP0875F)

Datasheet
This membrane protein is Human IL-7 R alpha / CD127 (23-1141(ITGA11)&21-728(ITGB1)). It has been tested in SDS-PAGE, ELISA, SPR. We provide this protein to facilitate your membrane protein antibody discovery and development.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • IL-7 R alpha / CD127
  • Protein Length
  • ECD
  • Molecular Weight
  • The protein has a calculated MW of 52.0 kDa. The protein migrates as 65-115 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
  • Sequence
  • AA Glu 21 - Gly 236 (Accession # P16871-1).

Product Description

  • Activity
  • Yes
  • Application
  • SDS-PAGE, ELISA, SPR
  • Expression Systems
  • HEK293
  • Tag
  • Mouse IgG2a Fc tag at the C-terminus
  • Protein Format
  • Soluble
  • Reconstitution
  • Please see Certificate of Analysis for specific instructions.
  • Endotoxin
  • <1.0 EU/μg by the LAL method
  • Purity
  • >90% as determined by SDS-PAGE.
  • Buffer
  • Lyophilized from 0.22 μm filtered solution in Tris with Glycine, Arginine and NaCl, pH7.5. Normally trehalose is added as protectant before lyophilization.

Target

  • Target Protein
  • IL-7 R alpha / CD127
  • Full Name
  • interleukin 7 receptor
  • Introduction
  • The protein encoded by this gene is a receptor for interleukin 7 (IL7). The function of this receptor requires the interleukin 2 receptor, gamma chain (IL2RG), which is a common gamma chain shared by the receptors of various cytokines, including interleukins 2, 4, 7, 9, and 15. This protein has been shown to play a critical role in V(D)J recombination during lymphocyte development. Defects in this gene may be associated with severe combined immunodeficiency (SCID). Alternatively spliced transcript variants have been found.
  • Alternative Names
  • ILRA; CD127; IL7RA; CDW127; IL-7R-alpha; interleukin-7 receptor subunit alpha; CD127 antigen; IL-7 receptor subunit alpha; IL-7R subunit alpha; interleukin 7 receptor alpha chain

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