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Magic™ Antibody Discovery - Human Lipocalin-2 / NGAL (21-198) Membrane Protein, Partial, -His tag (CAT#: MP0566F)

Datasheet
This membrane protein is Human Lipocalin-2 / NGAL (21-198). It has been tested in SDS-PAGE. We provide this protein to facilitate your membrane protein antibody discovery and development.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • Lipocalin-2 / NGAL
  • Protein Length
  • ECD
  • Molecular Weight
  • The protein has a calculated MW of 21.4 kDa. The protein migrates as 23-25 kDa under reducing (R) condition (SDS-PAGE).
  • Sequence
  • AA Gln 21 - Gly 198 (Accession # NP_005555.2).

Product Description

  • Application
  • SDS-PAGE
  • Expression Systems
  • HEK293
  • Tag
  • His tag at the C-terminus
  • Protein Format
  • Soluble
  • Reconstitution
  • Please see Certificate of Analysis for specific instructions.
  • Endotoxin
  • <1.0 EU/μg by the LAL method
  • Purity
  • >95% as determined by SDS-PAGE.
  • Buffer
  • Lyophilized from 0.22 μm filtered solution in PBS, pH7.4. Normally trehalose is added as protectant before lyophilization.

Target

  • Target Protein
  • Lipocalin-2 / NGAL
  • Full Name
  • lipocalin 2
  • Introduction
  • This gene encodes a protein that belongs to the lipocalin family. Members of this family transport small hydrophobic molecules such as lipids, steroid hormones and retinoids. The protein encoded by this gene is a neutrophil gelatinase-associated lipocalin and plays a role in innate immunity by limiting bacterial growth as a result of sequestering iron-containing siderophores. The presence of this protein in blood and urine is an early biomarker of acute kidney injury. This protein is thought to be be involved in multiple cellular processes, including maintenance of skin homeostasis, and suppression of invasiveness and metastasis. Mice lacking this gene are more susceptible to bacterial infection than wild type mice.
  • Alternative Names
  • p25; 24p3; MSFI; NGAL; neutrophil gelatinase-associated lipocalin; 25 kDa alpha-2-microglobulin-related subunit of MMP-9; migration-stimulating factor inhibitor; oncogene 24p3; siderocalin LCN2

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