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Magic™ Antibody Discovery - Human MBL (21-248) Membrane Protein, Partial, -His tag (CAT#: MP0630F)

Datasheet
This membrane protein is Human MBL (21-248). It has been tested in SDS-PAGE. We provide this protein to facilitate your membrane protein antibody discovery and development.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • MBL
  • Protein Length
  • ECD
  • Molecular Weight
  • The protein has a calculated MW of 25.9 kDa. The protein migrates as 30-33 kDa under reducing (R) condition (SDS-PAGE).
  • Sequence
  • AA Glu 21 - Ile 248 (Accession # P11226-1).

Product Description

  • Application
  • SDS-PAGE
  • Expression Systems
  • HEK293
  • Tag
  • His tag at the C-terminus
  • Protein Format
  • Soluble
  • Reconstitution
  • Please see Certificate of Analysis for specific instructions.
  • Endotoxin
  • <1.0 EU/μg by the LAL method
  • Purity
  • >95% as determined by SDS-PAGE
  • Buffer
  • Lyophilized from 0.22 μm filtered solution in PBS, pH7.4. Normally trehalose is added as protectant before lyophilization.

Target

  • Target Protein
  • MBL
  • Full Name
  • mannose binding lectin 2
  • Introduction
  • This gene encodes the soluble mannose-binding lectin or mannose-binding protein found in serum. The protein encoded belongs to the collectin family and is an important element in the innate immune system. The protein recognizes and binds to mannose and N-acetylglucosamine on many microorganisms, including bacteria, yeast, and viruses including influenza virus, HIV and SARS-CoV. This binding activates the classical complement pathway. Deficiencies of this gene have been associated with susceptibility to autoimmune and infectious diseases.
  • Alternative Names
  • MBL; MBP; MBP1; MBPD; MBL2D; MBP-C; COLEC1; HSMBPC; mannose-binding protein C; collectin-1; mannan-binding lectin; mannose-binding lectin (protein C) 2, soluble (opsonic defect); mannose-binding lectin 2, soluble (opsonic defect)

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