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Magic™ Antibody Discovery - Human Nectin-3 / CD113 (58-400) Membrane Protein, Partial, -hIgG1 Fc tag (CAT#: MP0697F)

Datasheet
This membrane protein is Human Nectin-3 / CD113 (58-400). It has been tested in SDS-PAGE, ELISA, BLI. We provide this protein to facilitate your membrane protein antibody discovery and development.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • Nectin-3 / CD113
  • Protein Length
  • ECD
  • Molecular Weight
  • The protein has a calculated MW of 64.3 kDa. The protein migrates as 80-95 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
  • Sequence
  • AA Gly 58 - Asp 400 (Accession # Q9NQS3).

Product Description

  • Activity
  • Yes
  • Application
  • SDS-PAGE, ELISA, BLI
  • Expression Systems
  • HEK293
  • Tag
  • Human IgG1 Fc tag at the C-terminus
  • Protein Format
  • Soluble
  • Reconstitution
  • Please see Certificate of Analysis for specific instructions.
  • Endotoxin
  • <1.0 EU/μg by the LAL method
  • Purity
  • >95% as determined by SDS-PAGE.
  • Buffer
  • Lyophilized from 0.22 μm filtered solution in Tris with Glycine, Arginine and NaCl, pH7.5. Normally trehalose is added as protectant before lyophilization.

Target

  • Target Protein
  • Nectin-3 / CD113
  • Full Name
  • nectin cell adhesion molecule 3
  • Introduction
  • This gene encodes a member of the nectin family of proteins, which function as adhesion molecules at adherens junctions. This family member interacts with other nectin-like proteins and with afadin, a filamentous actin-binding protein involved in the regulation of directional motility, cell proliferation and survival. This gene plays a role in ocular development involving the ciliary body. Mutations in this gene are believed to result in congenital ocular defects. Alternative splicing results in multiple transcript variants.
  • Alternative Names
  • PPR3; PRR3; CD113; PVRL3; PVRR3; CDW113; NECTIN-3; nectin-3; nectin 3; poliovirus receptor-related 3; poliovirus receptor-related protein 3

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