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Magic™ Antibody Discovery - Human NME1 / NDKA / NM23-H1 (2-152) Membrane Protein, Partial, His- tag (CAT#: MP0681F)

This membrane protein is Human NME1 / NDKA / NM23-H1 (2-152). It has been tested in SDS-PAGE. We provide this protein to facilitate your membrane protein antibody discovery and development.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • NME1 / NDKA / NM23-H1
  • Protein Length
  • ECD
  • Molecular Weight
  • The protein has a calculated MW of 18.0 kDa. The protein migrates as 21 kDa under reducing (R) condition (SDS-PAGE).
  • Sequence
  • AA Ala 2 - Glu 152 (Accession # AAH00293).

Product Description

  • Application
  • SDS-PAGE
  • Expression Systems
  • E.coli
  • Tag
  • His tag at the N-terminus
  • Protein Format
  • Soluble
  • Reconstitution
  • Please see Certificate of Analysis for specific instructions.
  • Endotoxin
  • <1.0 EU/μg by the LAL method
  • Purity
  • >98% as determined by SDS-PAGE.
  • Buffer
  • Lyophilized from 0.22 μm filtered solution in PBS, pH7.4. Normally trehalose is added as protectant before lyophilization.

Target

  • Target Protein
  • NME1 / NDKA / NM23-H1
  • Full Name
  • NME/NM23 nucleoside diphosphate kinase 1
  • Introduction
  • This gene (NME1) was identified because of its reduced mRNA transcript levels in highly metastatic cells. Nucleoside diphosphate kinase (NDK) exists as a hexamer composed of 'A' (encoded by this gene) and 'B' (encoded by NME2) isoforms. Mutations in this gene have been identified in aggressive neuroblastomas. Two transcript variants encoding different isoforms have been found for this gene. Co-transcription of this gene and the neighboring downstream gene (NME2) generates naturally-occurring transcripts (NME1-NME2), which encodes a fusion protein comprised of sequence sharing identity with each individual gene product.
  • Alternative Names
  • NB; AWD; NBS; GAAD; NDKA; NM23; NDPKA; NDPK-A; NM23-H1; nucleoside diphosphate kinase A; NDP kinase A; epididymis secretory sperm binding protein; granzyme A-activated DNase; metastasis inhibition factor nm23; non-metastatic cells 1, protein (NM23A) expressed in; tumor metastatic process-associated protein

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