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Magic™ Antibody Discovery - Human PTH1R / PTHR1 (27-188) Membrane Protein, Partial, -His tag (CAT#: MP0783F)

Datasheet
This membrane protein is Human PTH1R / PTHR1 (27-188). It has been tested in SDS-PAGE. We provide this protein to facilitate your membrane protein antibody discovery and development.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • PTH1R / PTHR1
  • Protein Length
  • ECD
  • Molecular Weight
  • The protein has a calculated MW of 19.6 kDa. The protein migrates as 27-43 kDa under reducing (R) condition (SDS-PAGE) due to different glycosylation.
  • Sequence
  • AA Asp 27 - Gly 188 (Accession # Q03431-1).

Product Description

  • Application
  • SDS-PAGE
  • Expression Systems
  • HEK293
  • Tag
  • His tag at the C-terminus
  • Protein Format
  • Soluble
  • Reconstitution
  • Please see Certificate of Analysis for specific instructions.
  • Endotoxin
  • <1.0 EU/μg by the LAL method
  • Purity
  • >85% as determined by SDS-PAGE.
  • Buffer
  • Lyophilized from 0.22 μm filtered solution in PBS, pH7.4. Normally trehalose is added as protectant before lyophilization.

Target

  • Target Protein
  • PTH1R / PTHR1
  • Full Name
  • parathyroid hormone 1 receptor
  • Introduction
  • The protein encoded by this gene is a member of the G-protein coupled receptor family 2. This protein is a receptor for parathyroid hormone (PTH) and for parathyroid hormone-like hormone (PTHLH). The activity of this receptor is mediated by G proteins which activate adenylyl cyclase and also a phosphatidylinositol-calcium second messenger system. Defects in this receptor are known to be the cause of Jansen's metaphyseal chondrodysplasia (JMC), chondrodysplasia Blomstrand type (BOCD), as well as enchodromatosis. Two transcript variants encoding the same protein have been found for this gene.
  • Alternative Names
  • PFE; EKNS; PTHR; PTHR1; parathyroid hormone/parathyroid hormone-related peptide receptor; PTH/PTHr receptor; PTH/PTHrP type I receptor; PTH1 receptor; parathyroid hormone receptor 1; parathyroid hormone/parathyroid hormone-related protein receptor; seven transmembrane helix receptor

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