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Magic™ Antibody Discovery - Human RAGE / AGER (23-344) Membrane Protein, Partial, hIgG1 Fc tag (CAT#: MP0811F)

Datasheet
This membrane protein is Human RAGE / AGER (1-673). It has been tested in SDS-PAGE, ELISA. We provide this protein to facilitate your membrane protein antibody discovery and development.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • RAGE / AGER
  • Protein Length
  • ECD
  • Molecular Weight
  • The protein has a calculated MW of 60.8 kDa. The protein migrates as 80 - 90 kDa and 35 kDa Fc fragment under reducing (R) condition (SDS-PAGE) due to glycosylation and auto-cleavage.
  • Sequence
  • AA Ala 23 - Ala 344 (Accession # NP_001127)

Product Description

  • Activity
  • Yes
  • Application
  • SDS-PAGE, ELISA
  • Expression Systems
  • HEK293
  • Tag
  • Human IgG1 Fc tag at the C-terminus
  • Protein Format
  • Soluble
  • Reconstitution
  • Please see Certificate of Analysis for specific instructions.
  • Endotoxin
  • <1.0 EU/μg by the LAL method
  • Purity
  • >60% as determined by SDS-PAGE.
  • Buffer
  • Lyophilized from 0.22 μm filtered solution in 50 mM Tris, 100 mM Glycine, pH7.5. Normally trehalose is added as protectant before lyophilization.

Target

  • Target Protein
  • RAGE / AGER
  • Full Name
  • advanced glycosylation end-product specific receptor
  • Introduction
  • The advanced glycosylation end product (AGE) receptor encoded by this gene is a member of the immunoglobulin superfamily of cell surface receptors. It is a multiligand receptor, and besides AGE, interacts with other molecules implicated in homeostasis, development, and inflammation, and certain diseases, such as diabetes and Alzheimer's disease. Many alternatively spliced transcript variants encoding different isoforms, as well as non-protein-coding variants, have been described for this gene
  • Alternative Names
  • RAGE; SCARJ1; advanced glycosylation end product-specific receptor; receptor for advanced glycation end-products variant 20

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