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Magic™ Antibody Discovery - Human SCARB1 / SR-B1 (33-443) Membrane Protein, Partial, -hIgG1 Fc tag (CAT#: MP0391F)

Datasheet
This membrane protein is Human SCARB1 / SR-B1 (33-443). It has been tested in SDS-PAGE. We provide this protein to facilitate your membrane protein antibody discovery and development.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • SCARB1 / SR-B1
  • Protein Length
  • ECD
  • Molecular Weight
  • The protein has a calculated MW of 72.7 kDa. As a result of glycosylation, the protein migrates as 110-115 kDa under reducing (R) condition, and 220-230 kDa under non-reducing (NR) condition (SDS-PAGE).
  • Sequence
  • AA Pro 33 - Tyr 443 (Accession # NP_005496.4).

Product Description

  • Application
  • SDS-PAGE
  • Expression Systems
  • HEK293
  • Tag
  • Human IgG1 Fc tag at the C-terminus
  • Protein Format
  • Soluble
  • Reconstitution
  • Please see Certificate of Analysis for specific instructions.
  • Endotoxin
  • <1.0 EU/μg by the LAL method
  • Purity
  • >95% as determined by SDS-PAGE.
  • Buffer
  • Lyophilized from 0.22 μm filtered solution in 50 mM Tris, 100 mM Glycine, pH7.5. Normally trehalose is added as protectant before lyophilization.

Target

  • Target Protein
  • SCARB1 / SR-B1
  • Full Name
  • scavenger receptor class B member 1
  • Introduction
  • The protein encoded by this gene is a plasma membrane receptor for high density lipoprotein cholesterol (HDL). The encoded protein mediates cholesterol transfer to and from HDL. In addition, this protein is a receptor for hepatitis C virus glycoprotein E2. Several transcript variants encoding different isoforms have been found for this gene.
  • Alternative Names
  • CLA1; SRB1; CLA-1; SR-BI; CD36L1; HDLQTL6; scavenger receptor class B member 1; CD36 and LIMPII analogous 1; CD36 antigen (collagen type I receptor, thrombospondin receptor)-like 1; scavenger receptor class B type III

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