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Magic™ Antibody Discovery - Mouse BCMA / TNFRSF17 (1-49) Membrane Protein, Partial, -hIgG1 Fc tag (CAT#: MP0990F)

Datasheet
This membrane protein is Mouse BCMA / TNFRSF17 (1-49). It has been tested in SDS-PAGE, ELISA. We provide this protein to facilitate your membrane protein antibody discovery and development.

Product Specifications

  • Host Species
  • Mouse
  • Target Protein
  • BCMA / TNFRSF17
  • Protein Length
  • ECD
  • Molecular Weight
  • The protein has a calculated MW of 32.1 kDa. The protein migrates as 36 kDa under reducing (R) condition (SDS-PAGE) due to O-linked glycosylation which has been verified by O-Glycosidase and Neuraminidase digestion.
  • Sequence
  • AA Met 1 - Thr 49 (Accession # O88472-1).

Product Description

  • Activity
  • Yes
  • Application
  • SDS-PAGE, ELISA
  • Expression Systems
  • HEK293
  • Tag
  • Human IgG1 Fc tag at the C-terminus
  • Protein Format
  • Soluble
  • Reconstitution
  • Please see Certificate of Analysis for specific instructions.
  • Endotoxin
  • <1.0 EU/μg by the LAL method
  • Purity
  • >95% as determined by SDS-PAGE.
  • Buffer
  • Lyophilized from 0.22 μm filtered solution in Tris with Glycine, Arginine and NaCl, pH7.5. Normally trehalose is added as protectant before lyophilization.

Target

  • Target Protein
  • BCMA / TNFRSF17
  • Full Name
  • tumor necrosis factor receptor superfamily, member 17
  • Introduction
  • The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is preferentially expressed in mature B lymphocytes, and may be important for B cell development and autoimmune response. This receptor has been shown to specifically bind to the tumor necrosis factor (ligand) superfamily, member 13b (TNFSF13B/TALL-1/BAFF), and to lead to NF-kappaB and MAPK8/JNK activation. This receptor also binds to various TRAF family members, and thus may transduce signals for cell survival and proliferation.
  • Alternative Names
  • BCM; BCMA; Tnfrs; Tnfrsf13; Tnfrsf13a; tumor necrosis factor receptor superfamily member 17; B-cell maturation protein

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