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Magic™ Antibody Discovery - Mouse IL-17A / CTLA-8 (26-158) Membrane Protein, Partial, His- tag (CAT#: MP0301F)

This membrane protein is Mouse IL-17A / CTLA-8 (26-158). It has been tested in SDS-PAGE, ELISA, Cell based assay, SEC-SEC-MALS, BLI. We provide this protein to facilitate your membrane protein antibody discovery and development.

Product Specifications

  • Host Species
  • Mouse
  • Target Protein
  • IL-17A / CTLA-8
  • Protein Length
  • ECD
  • Molecular Weight
  • The protein has a calculated MW of 15.8 kDa. The protein migrates as 18 kDa, 20-23 kDa and 26 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
  • Sequence
  • AA Ala 26 - Ala 158 (Accession # Q62386-1).

Product Description

  • Activity
  • Yes
  • Application
  • SDS-PAGE, ELISA, Cell based assay, SEC-SEC-MALS, BLI
  • Expression Systems
  • HEK293
  • Tag
  • His tag at the N-terminus
  • Protein Format
  • Soluble
  • Reconstitution
  • Please see Certificate of Analysis for specific instructions.
  • Endotoxin
  • <1.0 EU/μg by the LAL method
  • Purity
  • >90% as determined by SDS-PAGE.
  • Buffer
  • Lyophilized from 0.22 μm filtered solution in PBS, pH7.4. Normally trehalose is added as protectant before lyophilization.

Target

  • Target Protein
  • IL-17A / CTLA-8
  • Full Name
  • interleukin 17A
  • Introduction
  • This gene encodes a pro-inflammatory cytokine that is a member of the interleukin-17 family. The encoded protein plays a central role in host defense against diverse pathogens. The encoded protein is produced by activated T-cells and certain cell types of innate immune system. The active protein functions as either a homodimer with other interleukin-17 family members and signals through the interleukin-17 receptor to induce inflammatory cytokine production. Aberrant expression of this gene is associated with autoinflammatory diseases including rheumatoid arthritis, psoriasis and multiple sclerosis.
  • Alternative Names
  • Il; Ctl; IL-; Ctla; Il17; Ctla8; IL-17; Ctla-8; IL-17A; interleukin-17A; cytotoxic T-lymphocyte-associated antigen 8

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