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Magic™ Antibody Discovery - Rat FcRn (FCGRT & B2M) (23-298(FCGRT)&21-119(B2M)) Membrane Protein, Partial, -Avi -His &-Twin-Strep Tag, [Biotin] (CAT#: MP1449F)

Datasheet
This membrane protein is Rat FcRn (FCGRT & B2M) (23-298(FCGRT)&21-119(B2M)). It has been tested in SDS-PAGE, SPR. We provide this protein to facilitate your membrane protein antibody discovery and development.

Product Specifications

  • Host Species
  • Rat
  • Target Protein
  • FcRn (FCGRT & B2M)
  • Protein Length
  • ECD
  • Molecular Weight
  • Biotinylated Rat FCGRT&B2M Heterodimer Protein, Avitag,His Tag&Strep II Tag (SPR verified), produced by co-expression of FCGRT and B2M, has a calculated MW of 34.7 kDa (FCGRT) and 13.1 kDa (B2M). Subunit FCGRT is fused with an Avi tag at the C-terminus, followed by a polyhistidine tag and subunit Beta-2 microglobulin (B2M) is fused with a Strep II tag at the C-terminus. The reducing (R) protein migrates as 45-50 kDa (FCGRT) and 14 kDa (B2M) respectively due to different glycosylation.
  • Sequence
  • AA Ala 23 - Ser 298 (FCGRT) & Ile 21 - Met 119 (B2M) (Accession # P13599-1 (FCGRT) & P07151-1 (B2M)).

Product Description

  • Activity
  • Yes
  • Application
  • SDS-PAGE, SPR
  • Expression Systems
  • HEK293
  • Tag
  • Subunit FCGRT is fused with an Avi tag at the C-terminus, followed by a His tag and subunit Beta-2 microglobulin (B2M) is fused with a Strep II tag at the C-terminus
  • Protein Format
  • Soluble
  • Reconstitution
  • Please see Certificate of Analysis for specific instructions.
  • Endotoxin
  • <1.0 EU/μg by the LAL method
  • Purity
  • >95% as determined by SDS-PAGE
  • Buffer
  • Lyophilized from 0.22 μm filtered solution in PBS, pH7.4. Normally trehalose is added as protectant before lyophilization.

Target

  • Target Protein
  • FcRn (FCGRT & B2M)
  • Full Name
  • Fc fragment of IgG receptor and transporter&beta-2-microglobulin
  • Introduction
  • binds and transports maternal immunoglobulin gamma from milk; plays a role in providing maternal immunity to neonates
  • Alternative Names
  • FCRN, alpha-chain, IgG receptor FcRn large subunit p51, Fc fragment of IgG, receptor, transporter, alpha, FcRn alpha chain, IgG Fc fragment receptor transporter alpha chain, heavy chain of the major histocompatibility complex class I-like Fc receptor, immunoglobulin receptor, intestinal, heavy chain, major histocompatibility complex class I-like Fc receptor, neonatal Fc receptor, neonatal Fc-receptor for Ig, transmembrane alpha chain of the neonatal receptor

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