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Magic™ Human CD28 Jurkat Cell Line with NFAT-Luc Reporter (CAT#: S01YF-0123-KX446)

This product is a Jurkat stable cell line. It stably expresses Human CD28 to provide cell models for research and screening applications.

Product Information

  • Target Protein
  • CD28
  • Target Protein Species
  • Human
  • Host Cell Type
  • Jurkat
  • Target Classification
  • CD
  • Target Family
  • CD
  • Target Research Area
  • Infectious Research; Inflammation Research
  • Related Diseases
  • Mycosis Fungoides; Sezary's Disease

Product Properties

  • Assay Types
  • Drug screening and biological assays
  • Assay Reporter
  • NFAT-Luc
  • Mycoplasma Testing
  • Negative
  • Biosafety Level
  • Level 1
  • Activity
  • Yes
  • Quantity
  • 3x10⁶ cells
  • Form
  • Frozen cells
  • Selective Antibiotic(s)
  • Regular antibiotics active against mycoplasmas, bacteria and fungi.
  • Handling Notes
  • Frozen cells should be thawed immediately upon receipt and grown according to handling procedure to ensure cell viability and proper assay performance.
    Note: Do not freeze the cells upon receipt as it may result in irreversible damage to the cell line.
    Disclaimer: We cannot guarantee cell viability if the cells are not thawed immediately upon receipt and grown according to handling procedure.
  • Incubation
  • 37°C with 5% CO₂
  • Applications
  • Drug screening and biological assays
  • Application Notes
  • Cells were plated in a 384-well plate and incubated overnight at 37°C and 5% CO₂ to allow the cells to attach and grow. Cells were then stimulated with a control for high-throughput drugs screening andfunctional assays.
  • Use Restrictions
  • These cells are distributed for research use only.
  • Shipping
  • Dry ice
  • Storage
  • Liquid nitrogen

Target

  • Full Name
  • CD28 molecule
  • Introduction
  • The protein encoded by this gene is essential for T-cell proliferation and survival, cytokine production, and T-helper type-2 development. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene.
  • Alternative Names
  • CD28; Tp44; T-cell-specific surface glycoprotein CD28; CD28 molecule

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