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Magic™ Human CSF3R (T618I) BaF3 Cell Line (CAT#: S01YF-0324-KX183)

This product is a BaF3 stable cell line. It stably expresses Human CSF3R (T618I) to provide cell models for research and screening applications.

Product Information

  • Target Protein
  • CSF3R (T618I)
  • Target Protein Species
  • Human
  • Host Cell Type
  • BaF3
  • Target Classification
  • Kinases/Enzyme
  • Target Family
  • Kinases/Enzyme
  • Target Research Area
  • Cancer Research
  • Related Diseases
  • Neutrophilia; Neutropenia

Product Properties

  • Assay Types
  • Functional assay and biological assay
  • Stability
  • 16 passages
  • Mycoplasma Testing
  • Negative
  • Biosafety Level
  • Level 1
  • Activity
  • Yes
  • Form
  • Frozen cells
  • Freeze Medium
  • 90% FBS+10% DMSO
  • Culture Medium
  • RPMI-1640+10%FBS
  • Selective Antibiotic(s)
  • Regular antibiotics active against mycoplasmas, bacteria and fungi.
  • Handling Notes
  • Frozen cells should be thawed immediately upon receipt and grown according to handling procedure to ensure cell viability and proper assay performance.
    Note: Do not freeze the cells upon receipt as it may result in irreversible damage to the cell line.
    Disclaimer: We cannot guarantee cell viability if the cells are not thawed immediately upon receipt and grown according to handling procedure.
  • Incubation
  • 37°C with 5% CO₂
  • Applications
  • Anti-proliferation assay and PD assay
  • Application Notes
  • Cells were plated in a 384-well plate and incubated overnight at 37°C and 5% CO₂ to allow the cells to attach and grow. Cells were then stimulated with a control for high-throughput drugs screening andfunctional assays.
  • Use Restrictions
  • These cells are distributed for research use only.
  • Shipping
  • Dry ice
  • Storage
  • Liquid nitrogen

Target

  • Full Name
  • Colony stimulating factor 3 receptor
  • Introduction
  • The protein encoded by this gene is the receptor for colony stimulating factor 3, a cytokine that controls the production, differentiation, and function of granulocytes. The encoded protein, which is a member of the family of cytokine receptors, may also function in some cell surface adhesion or recognition processes. Alternatively spliced transcript variants have been described. Mutations in this gene are a cause of Kostmann syndrome, also known as severe congenital neutropenia.
  • Alternative Names
  • CSF3R; SCN7; CD114; GCSFR; granulocyte colony-stimulating factor receptor; CD114 antigen; G-CSF receptor; G-CSF-R; colony stimulating factor 3 receptor (granulocyte); Colony stimulating factor 3 receptor
  • Gene ID
  • 1441
  • UniProt ID
  • Q99062

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