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Magic™ Human TLR9 HEK293 Cell Line with SEAP Reporter (CAT#: S01YF-0123-KX409)

This product is a HEK293 stable cell line. It stably expresses Human TLR9 to provide cell models for research and screening applications.

Product Information

  • Target Protein
  • TLR9
  • Target Protein Species
  • Human
  • Host Cell Type
  • HEK293
  • Target Classification
  • Immune Checkpoint
  • Target Family
  • Immune Checkpoint
  • Target Research Area
  • Inflammation Research; Metabolic Research
  • Related Diseases
  • Cervicitis; Esophageal Atresia

Product Properties

  • Morphology
  • Adherent
  • Assay Types
  • Drug screening and biological assays
  • Assay Reporter
  • SEAP
  • Mycoplasma Testing
  • Negative
  • Biosafety Level
  • Level 1
  • Activity
  • Yes
  • Quantity
  • 3x10⁶ cells
  • Form
  • Frozen cells
  • Selective Antibiotic(s)
  • Regular antibiotics active against mycoplasmas, bacteria and fungi.
  • Handling Notes
  • Frozen cells should be thawed immediately upon receipt and grown according to handling procedure to ensure cell viability and proper assay performance.
    Note: Do not freeze the cells upon receipt as it may result in irreversible damage to the cell line.
    Disclaimer: We cannot guarantee cell viability if the cells are not thawed immediately upon receipt and grown according to handling procedure.
  • Incubation
  • 37°C with 5% CO₂
  • Applications
  • Drug screening and biological assays
  • Application Notes
  • Cells were plated in a 384-well plate and incubated overnight at 37°C and 5% CO₂ to allow the cells to attach and grow. Cells were then stimulated with a control for high-throughput drugs screening andfunctional assays.
  • Use Restrictions
  • These cells are distributed for research use only.
  • Shipping
  • Dry ice
  • Storage
  • Liquid nitrogen

Target

  • Full Name
  • Toll like receptor 9
  • Introduction
  • The protein encoded by this gene is a member of the Toll-like receptor (TLR) family, which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. Studies in mice and human indicate that this receptor mediates cellular response to unmethylated CpG dinucleotides in bacterial DNA to mount an innate immune response.
  • Alternative Names
  • TLR9; CD289; toll-like receptor 9; UNQ5798/PRO19605; Toll like receptor 9

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