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Magic™ Membrane Protein Bacterial Escherichia coli-EspH (Cytoskeleton-modulating effector of enterohaemorrhagic and enteropathogenic Escherichia coli-EspH) (CAT#: MP0013F)

EspH represses filopodium formation and enhances the formation of pedestals. EspH induces actin polymerization at the bacterial attachment sites during Enteropathogenic.

Product Specifications

  • Host Species
  • Bacterial
  • Target Protein
  • Escherichia coli-EspH
  • Protein Length
  • Full Length
  • Protein Class
  • Transporter
  • Molecular Weight
  • 36.7kDa
  • TMD
  • 6

Product Description

  • Activity
  • To be tested
  • Application
  • Screening & display technologies
  • Expression Systems
  • Cell-free expression system in the presence of lipid vesicles
  • Tag
  • Histidine tag fused to the N-terminal end of the protein
  • Protein Format
  • Proteoliposome
  • Purification
  • Sucrose gradient
  • Purity
  • >60% by SDS-Page and Coomassie Blue staining
  • Buffer
  • Tris 50mM, pH 7.5

Target

  • Target Protein
  • Escherichia coli-EspH
  • Full Name
  • Cytoskeleton-modulating effector of enterohaemorrhagic and enteropathogenic Escherichia coli-EspH
  • Introduction
  • EspH is a new cytoskeleton-modulating effector of enterohaemorrhagic and enteropathogenic Escherichia coli.
  • Alternative Names
  • Escherichia coli-EspH
  • UniProt ID

Customer reviews and Q&As    

Q&As

What accounts for the ability of EspH to regulate the actin cytoskeleton?

Related studies suggest that this may be due to its ability to bind and inhibit the Dbl homology-prenyl homology (DH-PH) structural domain of Rho guanine nucleotide exchange factors (RhoGEFs). Other effects attributed to EspH include focal adhesion disassembly to trigger host detachment and activation of cysteinase-3 to promote host cytotoxicity and death.
2022-12-21

All listed services and products are For Research Use Only. Do Not use in any diagnostic or therapeutic applications.

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