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Magic™ Membrane Protein Biotinylated Human PROM1 (Prominin 1) Expressed in HEK293, Nanodisc, Full Length (CAT#: MPX0387K)

This product is a 98.9 kDa Biotinylated Human PROM1 membrane protein expressed in HEK293. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • PROM1
  • Protein Length
  • Partial (20-865 aa)
  • Protein Class
  • Receptor
  • Molecular Weight
  • 98.9 kDa
  • TMD
  • 5
  • Sequence
  • GGQPSSTDAPKAWNYELPATNYETQDSHKAG
    PIGILFELVHIFLYVVQPRDFPEDTLRKFLQKAYESKIDYDKPETVILGL
    KIVYYEAGIILCCVLGLLFIILMPLVGYFFCMCRCCNKCGGEMHQRQKEN
    GPFLRKCFAISLLVICIIISIGIFYGFVANHQVRTRIKRSRKLADSNFKD
    LRTLLNETPEQIKYILAQYNTTKDKAFTDLNSINSVLGGGILDRLRPNII
    PVLDEIKSMATAIKETKEALENMNSTLKSLHQQSTQLSSSLTSVKTSLRS
    SLNDPLCLVHPSSETCNSIRLSLSQLNSNPELRQLPPVDAELDNVNNVLR
    TDLDGLVQQGYQSLNDIPDRVQRQTTTVVAGIKRVLNSIGSDIDNVTQRL
    PIQDILSAFSVYVNNTESYIHRNLPTLEEYDSYWWLGGLVICSLLTLIVI
    FYYLGLLCGVCGYDRHATPTTRGCVSNTGGVFLMVGVGLSFLFCWILMII
    VVLTFVFGANVEKLICEPYTSKELFRVLDTPYLLNEDWEYYLSGKLFNKS
    KMKLTFEQVYSDCKKNRGTYGTLHLQNSFNISEHLNINEHTGSISSELES
    LKVNLNIFLLGAAGRKNLQDFAACGIDRMNYDSYLAQTGKSPAGVNLLSF
    AYDLEAKANSLPPGNLRNSLKRDAQTIKTIHQQRVLPIEQSLSTLYQSVK
    ILQRTGNGLLERVTRILASLDFAQNFITNNTSSVIIEETKKYGRTIIGYF
    EHYLQWIEFSISEKVASCKPVATALDTAVDVFLCSYIIDPLNLFWFGIGK
    ATVFLLPALIFAVKLAKYYRRMDSEDVYDDVETIPMKNMENGNNGYHKDH
    VYGIHNPVMTSPSQH

Product Description

  • Expression Systems
  • HEK293
  • Tag
  • His and Avi tag at the C-terminus
  • Protein Format
  • Nanodisc

Target

  • Target Protein
  • PROM1
  • Full Name
  • Prominin 1
  • Introduction
  • This gene encodes a pentaspan transmembrane glycoprotein. The protein localizes to membrane protrusions and is often expressed on adult stem cells, where it is thought to function in maintaining stem cell properties by suppressing differentiation. Mutations in this gene have been shown to result in retinitis pigmentosa and Stargardt disease. Expression of this gene is also associated with several types of cancer. This gene is expressed from at least five alternative promoters that are expressed in a tissue-dependent manner. Multiple transcript variants encoding different isoforms have been found for this gene.
  • Alternative Names
  • PROM1; RP41; AC133; CD133; MCDR2; STGD4; CORD12; PROML1; MSTP061; antigen AC133; hProminin; hematopoietic stem cell antigen; prominin-like protein 1; Prominin 1

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