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Magic™ Membrane Protein Escherichia coli ANXA7 (Annexin A7) for Antibody Discovery (CAT#: MP0036X)

Datasheet
This product is a 52.9 kDa Escherichia coli ANXA7 membrane protein expressed in in vitro wheat germ expression system. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Escherichia coli
  • Target Protein
  • ANXA7
  • Protein Length
  • Full-length
  • Molecular Weight
  • 52.9 kDa
  • Sequence
  • MGSSHHHHHHSSGLVPRGSHMGSHMSYPGYPPTGYPPFPGYPPAGQESSFPPSGQYPYPSGFPPMGGGAYPQVPSSGYPGAGGYPAPGGYPAPGGYPGAPQPGGAPSYPGVPPGQGFGVPPGGAGFSGYPQPPSQSYGGGPAQVPLPGGFPGGQMPSQYPGGQPTYPSQPATVTQVTQGTIRPAANFDAIRDAEILRKAMKGFGTDEQAIVDVVANRSNDQRQKIKAAFKTSYGKDLIKDLKSELSGNMEELILALFMPPTYYDAWSLRKAMQGAGTQERVLIEILCTRTNQEIREIVRCYQSEFGRDLEKDIRSDTSGHFERLLVSMCQGNRDENQSINHQMAQEDAQRLYQAGEGRLGTDESCFNMILATRSFPQLRATMEAYSRMANRDLLSSVSREFSGYVESGLKTILQCALNRPAFFAERLYYAMKGAGTDDSTLVRIVVTRSEIDLVQIKQMFAQMYQKTLGTMIAGDTSGDYRRLLLAIVGQ

Product Description

  • Application
  • SDS-PAGE
  • Expression Systems
  • in vitro wheat germ expression system
  • Tag
  • His tag expressed in Escherichia coli
  • Purity
  • > 85% by SDS-PAGE
  • Buffer
  • 20 mM Mes buffer, 0.15 M NaCl, pH 5.0 (40% glycerol, 1 mM DTT)

Target

  • Target Protein
  • ANXA7
  • Full Name
  • Annexin A7
  • Introduction
  • Annexin VII is a member of the annexin family of calcium-dependent phospholipid binding proteins.The Annexin VII gene contains 14 exons and spans approximately 34 kb of DNA. An alternatively spliced cassette exon results in two mRNA transcripts of 2.0 and 2.4 kb which are predicted to generate two protein isoforms differing in their N-terminal domain. The alternative splicing event is tissue specific and the mRNA containing the cassette exon is prevalent in brain, heart and skeletal muscle. The transcripts also differ in their 3'-non coding regions by the use of two alternative poly(A) signals. Annexin VII encodes a protein with a molecular weight of approximately 51 kDa with a unique, highly hydrophobic N-terminal domain of 167 amino acids and a conserved C-terminal region of 299 amino acids. The latter domain is composed of alternating hydrophobic and hydrophilic segments. Structural analysis of the protein suggests that Annexin VII is a membrane binding protein with diverse properties, including voltage-sensitive calcium channel activity, ion selectivity and membrane fusion
  • Alternative Names
  • ANX7; SNX; SYNEXIN; OTTHUMP00000019812; OTTHUMP00000019813; OTTHUMP00000042922; OTTHUMP00000042923; OTTHUMP00000042925; annexin VII

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