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Magic™ Membrane Protein Human ABCC11 (ATP binding cassette subfamily C member 11) Full Length (CAT#: MPC0351K) Made to Order

Datasheet
This product is a 154.3 kDa Human ABCC11 membrane protein expressed in HEK293. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • ABCC11
  • Protein Length
  • Full length
  • Protein Class
  • Transporter
  • Molecular Weight
  • 154.3 kDa
  • TMD
  • 10
  • Sequence
  • MTRKRTYWVPNSSGGLVNRGIDIGDDMVSGLIYKTYTLQDGPWSQQERNP
    EAPGRAAVPPWGKYDAALRTMIPFRPKPRFPAPQPLDNAGLFSYLTVSWL
    TPLMIQSLRSRLDENTIPPLSVHDASDKNVQRLHRLWEEEVSRRGIEKAS
    VLLVMLRFQRTRLIFDALLGICFCIASVLGPILIIPKILEYSEEQLGNVV
    HGVGLCFALFLSECVKSLSFSSSWIINQRTAIRFRAAVSSFAFEKLIQFK
    SVIHITSGEAISFFTGDVNYLFEGVCYGPLVLITCASLVICSISSYFIIG
    YTAFIAILCYLLVFPLAVFMTRMAVKAQHHTSEVSDQRIRVTSEVLTCIK
    LIKMYTWEKPFAKIIEDLRRKERKLLEKCGLVQSLTSITLFIIPTVATAV
    WVLIHTSLKLKLTASMAFSMLASLNLLRLSVFFVPIAVKGLTNSKSAVMR
    FKKFFLQESPVFYVQTLQDPSKALVFEEATLSWQQTCPGIVNGALELERN
    GHASEGMTRPRDALGPEEEGNSLGPELHKINLVVSKGMMLGVCGNTGSGK
    SSLLSAILEEMHLLEGSVGVQGSLAYVPQQAWIVSGNIRENILMGGAYDK
    ARYLQVLHCCSLNRDLELLPFGDMTEIGERGLNLSGGQKQRISLARAVYS
    DRQIYLLDDPLSAVDAHVGKHIFEECIKKTLRGKTVVLVTHQLQYLEFCG
    QIILLENGKICENGTHSELMQKKGKYAQLIQKMHKEATSDMLQDTAKIAE
    KPKVESQALATSLEESLNGNAVPEHQLTQEEEMEEGSLSWRVYHHYIQAA
    GGYMVSCIIFFFVVLIVFLTIFSFWWLSYWLEQGSGTNSSRESNGTMADL
    GNIADNPQLSFYQLVYGLNALLLICVGVCSSGIFTKVTRKASTALHNKLF
    NKVFRCPMSFFDTIPIGRLLNCFAGDLEQLDQLLPIFSEQFLVLSLMVIA
    VLLIVSVLSPYILLMGAIIMVICFIYYMMFKKAIGVFKRLENYSRSPLFS
    HILNSLQGLSSIHVYGKTEDFISQFKRLTDAQNNYLLLFLSSTRWMALRL
    EIMTNLVTLAVALFVAFGISSTPYSFKVMAVNIVLQLASSFQATARIGLE
    TEAQFTAVERILQYMKMCVSEAPLHMEGTSCPQGWPQHGEIIFQDYHMKY
    RDNTPTVLHGINLTIRGHEVVGIVGRTGSGKSSLGMALFRLVEPMAGRIL
    IDGVDICSIGLEDLRSKLSVIPQDPVLLSGTIRFNLDPFDRHTDQQIWDA
    LERTFLTKAISKFPKKLHTDVVENGGNFSVGERQLLCIARAVLRNSKIIL
    IDEATASIDMETDTLIQRTIREAFQGCTVLVIAHRVTTVLNCDHILVMGN
    GKVVEFDRPEVLRKKPGSLFAALMATATSSLR

Product Description

  • Expression Systems
  • HEK293
  • Tag
  • Flag-StrepII or based on specific requirements
  • Protein Format
  • Detergent or based on specific requirements

Target

  • Target Protein
  • ABCC11
  • Full Name
  • ATP binding cassette subfamily C member 11
  • Introduction
  • The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This ABC full transporter is a member of the MRP subfamily which is involved in multi-drug resistance. The product of this gene participates in physiological processes involving bile acids, conjugated steroids, and cyclic nucleotides. In addition, a SNP in this gene is responsible for determination of human earwax type. This gene and family member ABCC12 are determined to be derived by duplication and are both localized to chromosome 16q12.1. Multiple alternatively spliced transcript variants have been described for this gene.
  • Alternative Names
  • WW; EWWD; MRP8; ATP-binding cassette sub-family C member 11; ATP-binding cassette protein C11; ATP-binding cassette transporter MRP8; ATP-binding cassette transporter sub-family C member 11; ATP-binding cassette, sub-family C (CFTR/MRP), member 11; multi-resistance protein 8; multidrug resistance-associated protein 8; ABCC11; ATP binding cassette subfamily C member 11

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