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Magic™ Membrane Protein Human ABCD2 (ATP binding cassette subfamily D member 2) Full Length (CAT#: MPC1966K) Made to Order

Datasheet
This product is a 83.2 kDa Human ABCD2 membrane protein expressed in HEK293. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • ABCD2
  • Protein Length
  • Full length
  • Protein Class
  • Transporter
  • Molecular Weight
  • 83.2 kDa
  • TMD
  • 4
  • Sequence
  • MTHMLNAAADRVKWTRSSAAKRAACLVAAAYALKTLYPIIGKRLKQSGHG
    KKKAAAYPAAENTEILHCTETICEKPSPGVNADFFKQLLELRKILFPKLV
    TTETGWLCLHSVALISRTFLSIYVAGLDGKIVKSIVEKKPRTFIIKLIKW
    LMIAIPATFVNSAIRYLECKLALAFRTRLVDHAYETYFTNQTYYKVINMD
    GRLANPDQSLTEDIMMFSQSVAHLYSNLTKPILDVMLTSYTLIQTATSRG
    ASPIGPTLLAGLVVYATAKVLKACSPKFGKLVAEEAHRKGYLRYVHSRII
    ANVEEIAFYRGHKVEMKQLQKSYKALADQMNLILSKRLWYIMIEQFLMKY
    VWSSSGLIMVAIPIITATGFADGEDGQKQVMVSERTEAFTTARNLLASGA
    DAIERIMSSYKEVTELAGYTARVYNMFWVFDEVKRGIYKRTAVIQESESH
    SKNGAKVELPLSDTLAIKGKVIDVDHGIICENVPIITPAGEVVASRLNFK
    VEEGMHLLITGPNGCGKSSLFRILSGLWPVYEGVLYKPPPQHMFYIPQRP
    YMSLGSLRDQVIYPDSVDDMHDKGYTDQDLERILHNVHLYHIVQREGGWD
    AVMDWKDVLSGGEKQRMGMARMFYHKPKYALLDECTSAVSIDVEGKIFQA
    AKGAGISLLSITHRPSLWKYHTHLLQFDGEGGWRFEQLDTAIRLTLSEEK
    QKLESQLAGIPKMQQRLNELCKILGEDSVLKTIKNEDETS

Product Description

  • Expression Systems
  • HEK293
  • Tag
  • Flag-StrepII or based on specific requirements
  • Protein Format
  • Detergent or based on specific requirements

Target

  • Target Protein
  • ABCD2
  • Full Name
  • ATP binding cassette subfamily D member 2
  • Introduction
  • The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ALD subfamily, which is involved in peroxisomal import of fatty acids and/or fatty acyl-CoAs in the organelle. All known peroxisomal ABC transporters are half transporters which require a partner half transporter molecule to form a functional homodimeric or heterodimeric transporter. The function of this peroxisomal membrane protein is unknown; however this protein is speculated to function as a dimerization partner of ABCD1 and/or other peroxisomal ABC transporters. Mutations in this gene have been observed in patients with adrenoleukodystrophy, a severe demyelinating disease. This gene has been identified as a candidate for a modifier gene, accounting for the extreme variation among adrenoleukodystrophy phenotypes. This gene is also a candidate for a complement group of Zellweger syndrome, a genetically heterogeneous disorder of peroxisomal biogenesis.
  • Alternative Names
  • ABCD2; ALDR; ABC39; ALDL1; ALDRP; hALDR; ATP-binding cassette sub-family D member 2; ATP-binding cassette, sub-family D (ALD), member 2; adrenoleukodystrophy-like 1; adrenoleukodystrophy-related protein; ATP binding cassette subfamily D member 2

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