Magic™ Membrane Protein Human ABCE1 (ATP binding cassette subfamily E member 1) Full Length (CAT#: MPC0981K) Made to Order

Datasheet

This product is a 67.3 kDa Human ABCE1 membrane protein expressed in HEK293. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

Host Species
Human

Target Protein
ABCE1

Protein Length
Full length

Protein Class
Transporter

Molecular Weight
67.3 kDa

Sequence
MADKLTRIAIVNHDKCKPKKCRQECKKSCPVVRMGKLCIEVTPQSKIAWI
SETLCIGCGICIKKCPFGALSIVNLPSNLEKETTHRYCANAFKLHRLPIP
RPGEVLGLVGTNGIGKSTALKILAGKQKPNLGKYDDPPDWQEILTYFRGS
ELQNYFTKILEDDLKAIIKPQYVDQIPKAAKGTVGSILDRKDETKTQAIV
CQQLDLTHLKERNVEDLSGGELQRFACAVVCIQKADIFMFDEPSSYLDVK
QRLKAAITIRSLINPDRYIIVVEHDLSVLDYLSDFICCLYGVPSAYGVVT
MPFSVREGINIFLDGYVPTENLRFRDASLVFKVAETANEEEVKKMCMYKY
PGMKKKMGEFELAIVAGEFTDSEIMVMLGENGTGKTTFIRMLAGRLKPDE
GGEVPVLNVSYKPQKISPKSTGSVRQLLHEKIRDAYTHPQFVTDVMKPLQ
IENIIDQEVQTLSGGELQRVALALCLGKPADVYLIDEPSAYLDSEQRLMA
ARVVKRFILHAKKTAFVVEHDFIMATYLADRVIVFDGVPSKNTVANSPQT
LLAGMNKFLSQLEITFRRDPNNYRPRINKLNSIKDVEQKKSGNYFFLDD

Product Description

Expression Systems
HEK293

Tag
Flag-StrepII or based on specific requirements

Protein Format
Detergent or based on specific requirements

Target

Target Protein
ABCE1

Full Name
ATP binding cassette subfamily E member 1

Introduction
The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the OABP subfamily. Alternatively referred to as the RNase L inhibitor, this protein functions to block the activity of ribonuclease L. Activation of ribonuclease L leads to inhibition of protein synthesis in the 2-5A/RNase L system, the central pathway for viral interferon action. Two transcript variants encoding the same protein have been found for this gene.

Alternative Names
RLI; OABP; RLI1; ABC38; RNS4I; RNASEL1; RNASELI; ATP-binding cassette sub-family E member 1; 2'-5'-oligoadenylate-binding protein; ATP-binding cassette, sub-family E (OABP), member 1
RNase L inhibitor 1; huHP68; ribonuclease 4 inhibitor; ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent) inhibitor; ABCE1; ATP binding cassette subfamily E member 1

Gene ID
6059

UniProt ID
P61221

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