Close
Close

Magic™ Membrane Protein Human ABCG8 (ATP binding cassette subfamily G member 8) Full Length (CAT#: MPC0379K) Made to Order

Datasheet
This product is a 75.6 kDa Human ABCG8 membrane protein expressed in Komagataella pastoris. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • ABCG8
  • Protein Length
  • Full length
  • Protein Class
  • Transporter
  • Molecular Weight
  • 75.6 kDa
  • TMD
  • 6
  • Sequence
  • MAGKAAEERGLPKGATPQDTSGLQDRLFSSESDNSLYFTYSGQPNTLEVR
    DLNYQVDLASQVPWFEQLAQFKMPWTSPSCQNSCELGIQNLSFKVRSGQM
    LAIIGSSGCGRASLLDVITGRGHGGKIKSGQIWINGQPSSPQLVRKCVAH
    VRQHNQLLPNLTVRETLAFIAQMRLPRTFSQAQRDKRVEDVIAELRLRQC
    ADTRVGNMYVRGLSGGERRRVSIGVQLLWNPGILILDEPTSGLDSFTAHN
    LVKTLSRLAKGNRLVLISLHQPRSDIFRLFDLVLLMTSGTPIYLGAAQHM
    VQYFTAIGYPCPRYSNPADFYVDLTSIDRRSREQELATREKAQSLAALFL
    EKVRDLDDFLWKAETKDLDEDTCVESSVTPLDTNCLPSPTKMPGAVQQFT
    TLIRRQISNDFRDLPTLLIHGAEACLMSMTIGFLYFGHGSIQLSFMDTAA
    LLFMIGALIPFNVILDVISKCYSERAMLYYELEDGLYTTGPYFFAKILGE
    LPEHCAYIIIYGMPTYWLANLRPGLQPFLLHFLLVWLVVFCCRIMALAAA
    ALLPTFHMASFFSNALYNSFYLAGGFMINLSSLWTVPAWISKVSFLRWCF
    EGLMKIQFSRRTYKMPLGNLTIAVSGDKILSVMELDSYPLYAIYLIVIGL
    SGGFMVLYYVSLRFIKQKPSQDW

Product Description

  • Expression Systems
  • Komagataella pastoris
  • Tag
  • 12xHis tag at C-terminal
  • Protein Format
  • Detergent or based on specific requirements

Target

  • Target Protein
  • ABCG8
  • Full Name
  • ATP binding cassette subfamily G member 8
  • Introduction
  • The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the White subfamily. The protein encoded by this gene functions to exclude non-cholesterol sterol entry at the intestinal level, promote excretion of cholesterol and sterols into bile, and to facilitate transport of sterols back into the intestinal lumen. It is expressed in a tissue-specific manner in the liver, intestine, and gallbladder. This gene is tandemly arrayed on chromosome 2, in a head-to-head orientation with family member ABCG5. Mutations in this gene may contribute to sterol accumulation and atherosclerosis, and have been observed in patients with sitosterolemia.
  • Alternative Names
  • GBD4; STSL; STSL1; ATP-binding cassette sub-family G member 8; ATP-binding cassette, sub-family G (WHITE), member 8; sterolin 2; ABCG8; ATP binding cassette subfamily G member 8

Customer reviews and Q&As    

Related Products
Online Inquiry
CONTACT US
USA:
Europe:
Germany:
Call us at:
USA:
UK:
Germany:
Fax:
Email:
Our customer service representatives are available 24 hours a day, 7 days a week. Contact Us
© 2024 Creative Biolabs. | Contact Us