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Magic™ Membrane Protein Human AGRN (Agrin) Full Length (CAT#: MPC1280K) Made to Order

This product is a 217.3 kDa Human AGRN membrane protein expressed in HEK293. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • AGRN
  • Protein Length
  • Full length
  • Protein Class
  • Transporter
  • Molecular Weight
  • 217.3 kDa
  • Sequence
  • MAGRSHPGPLRPLLPLLVVAACVLPGAGGTCPERALERREEEANVVLTGT
    VEEILNVDPVQHTYSCKVRVWRYLKGKDLVARESLLDGGNKVVISGFGDP
    LICDNQVSTGDTRIFFVNPAPPYLWPAHKNELMLNSSLMRITLRNLEEVE
    FCVEDKPGTHFTPVPPTPPDACRGMLCGFGAVCEPNAEGPGRASCVCKKS
    PCPSVVAPVCGSDASTYSNECELQRAQCSQQRRIRLLSRGPCGSRDPCSN
    VTCSFGSTCARSADGLTASCLCPATCRGAPEGTVCGSDGADYPGECQLLR
    RACARQENVFKKFDGPCDPCQGALPDPSRSCRVNPRTRRPEMLLRPESCP
    ARQAPVCGDDGVTYENDCVMGRSGAARGLLLQKVRSGQCQGRDQCPEPCR
    FNAVCLSRRGRPRCSCDRVTCDGAYRPVCAQDGRTYDSDCWRQQAECRQQ
    RAIPSKHQGPCDQAPSPCLGVQCAFGATCAVKNGQAACECLQACSSLYDP
    VCGSDGVTYGSACELEATACTLGREIQVARKGPCDRCGQCRFGALCEAET
    GRCVCPSECVALAQPVCGSDGHTYPSECMLHVHACTHQISLHVASAGPCE
    TCGDAVCAFGAVCSAGQCVCPRCEHPPPGPVCGSDGVTYGSACELREAAC
    LQQTQIEEARAGPCEQAECGSGGSGSGEDGDCEQELCRQRGGIWDEDSED
    GPCVCDFSCQSVPGSPVCGSDGVTYSTECELKKARCESQRGLYVAAQGAC
    RGPTFAPLPPVAPLHCAQTPYGCCQDNITAARGVGLAGCPSACQCNPHGS
    YGGTCDPATGQCSCRPGVGGLRCDRCEPGFWNFRGIVTDGRSGCTPCSCD
    PQGAVRDDCEQMTGLCSCKPGVAGPKCGQCPDGRALGPAGCEADASAPAT
    CAEMRCEFGARCVEESGSAHCVCPMLTCPEANATKVCGSDGVTYGNECQL
    KTIACRQGLQISIQSLGPCQEAVAPSTHPTSASVTVTTPGLLLSQALPAP
    PGALPLAPSSTAHSQTTPPPSSRPRTTASVPRTTVWPVLTVPPTAPSPAP
    SLVASAFGESGSTDGSSDEELSGDQEASGGGSGGLEPLEGSSVATPGPPV
    ERASCYNSALGCCSDGKTPSLDAEGSNCPATKVFQGVLELEGVEGQELFY
    TPEMADPKSELFGETARSIESTLDDLFRNSDVKKDFRSVRLRDLGPGKSV
    RAIVDVHFDPTTAFRAPDVARALLRQIQVSRRRSLGVRRPLQEHVRFMDF
    DWFPAFITGATSGAIAAGATARATTASRLPSSAVTPRAPHPSHTSQPVAK
    TTAAPTTRRPPTTAPSRVPGRRPPAPQQPPKPCDSQPCFHGGTCQDWALG
    GGFTCSCPAGRGGAVCEKVLGAPVPAFEGRSFLAFPTLRAYHTLRLALEF
    RALEPQGLLLYNGNARGKDFLALALLDGRVQLRFDTGSGPAVLTSAVPVE
    PGQWHRLELSRHWRRGTLSVDGETPVLGESPSGTDGLNLDTDLFVGGVPE
    DQAAVALERTFVGAGLRGCIRLLDVNNQRLELGIGPGAATRGSGVGECGD
    HPCLPNPCHGGAPCQNLEAGRFHCQCPPGRVGPTCADEKSPCQPNPCHGA
    APCRVLPEGGAQCECPLGREGTFCQTASGQDGSGPFLADFNGFSHLELRG
    LHTFARDLGEKMALEVVFLARGPSGLLLYNGQKTDGKGDFVSLALRDRRL
    EFRYDLGKGAAVIRSREPVTLGAWTRVSLERNGRKGALRVGDGPRVLGES
    PKSRKVPHTVLNLKEPLYVGGAPDFSKLARAAAVSSGFDGAIQLVSLGGR
    QLLTPEHVLRQVDVTSFAGHPCTRASGHPCLNGASCVPREAAYVCLCPGG
    FSGPHCEKGLVEKSAGDVDTLAFDGRTFVEYLNAVTESELANEIPVPETL
    DSGALHSEKALQSNHFELSLRTEATQGLVLWSGKATERADYVALAIVDGH
    LQLSYNLGSQPVVLRSTVPVNTNRWLRVVAHREQREGSLQVGNEAPVTGS
    SPLGATQLDTDGALWLGGLPELPVGPALPKAYGTGFVGCLRDVVVGRHPL
    HLLEDAVTKPELRPCPTP

Product Description

  • Expression Systems
  • HEK293
  • Tag
  • Flag-StrepII or based on specific requirements
  • Protein Format
  • Detergent or based on specific requirements

Target

  • Target Protein
  • AGRN
  • Full Name
  • Agrin
  • Introduction
  • This gene encodes one of several proteins that are critical in the development of the neuromuscular junction (NMJ), as identified in mouse knock-out studies. The encoded protein contains several laminin G, Kazal type serine protease inhibitor, and epidermal growth factor domains. Additional post-translational modifications occur to add glycosaminoglycans and disulfide bonds. In one family with congenital myasthenic syndrome affecting limb-girdle muscles, a mutation in this gene was found. Alternative splicing results in multiple transcript variants encoding different isoforms.
  • Alternative Names
  • AGRN; CMS8; AGRIN; CMSPPD; agrin proteoglycan; Agrin

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